Research output per year
Research output per year
Dr. Bert van Loo studied Molecular Sciences at Wageningen University (1994-1999) and obtained his PhD in Biochemistry from the University of Groningen in 2006 (Supervisor: Prof. Dick Janssen). In 2005 he moved to the department of Biochemistry of the University of Cambridge to work as a post-doc in the lab of Prof. Florian Hollfelder. After a short stay at Uppsala university in Sweden in 2013 he moved to the institute for Evolution and Biodiversity at the University of Münster in Germany where he was a post-doctoral project leader within the Molecular Evolution and Bioinformatics group of Prof. Erich Bornberg-Bauer until 2019. In January 2020 he joined the department of applied sciences at Northumbria University as a senior lecturer in Biochemistry.
His main interests are within the wider theme of adaptive enzyme evolution and harnessing knowledge from in vivo adaptation to inform protein engineering strategies. He is studying the evolution of substrate specificity between phospho- and sulfohydrolases, as well as the evolution of enzymes that degrade environmental pollutants.
Dr. Bert van Loo’s main interests are within the wider theme of adaptive enzyme evolution. He studies both natural and artificial laboratory enzyme evolution, with particular interest in the adaptive evolutionary processes in relation to substrate specificity. He uses several model systems for these studies, most prominently the divergent evolution of phospho- and sulfohydrolases in the alkaline phosphatase and metallo-β-lactamase superfamilies. In addition to the latter, he is also looking into the evolution of enzymes that degrade xenobiotic compounds, in particular man-made environmental pollutants such as halogenated hydrocarbons and plastics. In addition to studying the evolution of these enzymes, both in nature and in the laboratory, he aims to harness the knowledge from in vivo adaptation to inform protein engineering strategies.
Biochemistry, PhD, Molecular Engineering of Epoxide Hydrolase for Biocatalytic Application, University of Groningen
1 Apr 1999 → 13 Oct 2006
Award Date: 13 Oct 2006
Biochemistry, MSc, Wageningen University & Research
1 Sept 1994 → 31 Mar 1999
Award Date: 31 Mar 1999
University of Münster
1 May 2013 → 30 Apr 2019
Uppsala University
1 Feb 2013 → 30 Apr 2013
University of Cambridge
1 Apr 2005 → 31 Jan 2013
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review