Personal profile
Research interests
Dr Arends develops novel analysis methodologies and creates (open source) software for use in (systems) biology research, such as the addition of Multiple QTL Mapping (MQM) into R/qtl. Furthermore, Dr Arends his interests are in the development of novel computational method to support day to day biological research.
The focus of his research is computational methods in quantitative trait locus (QTL) analysis, data visualizations, and integration of big data sets in a useful / comprehensive manner. Open-source software he developed can be found on Github.
Biography
Dr Arends is an Associate Professor in Bioinformatics within the Department of Applied Sciences at Northumbria. He graduated from the University of Groningen with a BSc in Lifescience and Technology, a MSc in Molecular Biology, and a PhD in Bioinformatics in 2014.
Prior to joining Northumbria University, Dr Arends completed his postdoctoral research in Professor Gudrun A. Brockmann her lab at the Humboldt University in Berlin working on development of Bioinformatics tools for the analysis and integration of biological datasets. During the COVID-19 pandemic he live-streamed his lectures (R programming & Bioinformatics) for MSc and PhD students on his YouTube channel.
Education/Academic qualification
Bioinformatics, PhD, High-throughput Computational Methods and Software for Quantitative Trait Locus (QTL) Mapping
1 Jan 2010 → 30 Apr 2014
Award Date: 17 Oct 2014
Molecular Biology, MSc, Molecular Biology & Biotechnology - research variant, University of Groningen
1 Jan 2007 → 31 Dec 2009
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Collaborations and top research areas from the last five years
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R/qtl: high-throughput multiple QTL mapping
Arends, D., Prins, P., Jansen, R. C. & Broman, K. W., 1 Oct 2010, In: Bioinformatics. 26, 23, p. 2990-2992 3 p.Research output: Contribution to journal › Article › peer-review
331 Citations (Scopus) -
A platform for experimental precision medicine: The extended BXD mouse family
Ashbrook, D. G., Arends, D., Prins, P., Mulligan, M. K., Roy, S., Williams, E. G., Lutz, C. M., Valenzuela, A., Bohl, C. J., Ingels, J. F., McCarty, M. S., Centeno, A. G., Hager, R., Auwerx, J., Lu, L. & Williams, R. W., 17 Mar 2021, In: Cell Systems. 12, 3, p. 235-247.e9 23 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Citations (Scopus) -
Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line
Arends, D., Kärst, S., Heise, S., Korkuc, P., Hesse, D. & Brockmann, G. A., 4 Jan 2022, In: Genetics. 220, 1, 11 p., iyab192.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)45 Downloads (Pure) -
Genetic Modulation of Lifespan: Dynamic Effects, Sex Differences, and Body Weight Trade-offs
Arends, D., Ashbrook, D. G., Roy, S., Lu, L., Sloan, Z., Centeno, A. G., Lamour, K. H., de Magalhães, J. P., Prins, P., Broman, K. W., Sen, S., Mitchell, S. J., MacArthur, M. R., Akin, Ö. A., Auwerx, J., Bajwa, A., Diaz, V., Harrison, D. E., Strong, R. & Nelson, J. F. & 4 others, , 29 Apr 2025, (Submitted) bioRxiv, p. 1-49, 49 p.Research output: Working paper › Preprint
File17 Downloads (Pure) -
Relationship between intramuscular fat content in longissimus thoracis and hair fatty acids in finishing crossbred bulls
Wulf, R., Arends, D., Boldt, A., Schmidt, S., Maak, S., Dannenberger, D. & Brockmann, G. A., 27 Nov 2025, In: Scientific Reports. 15, 1, p. 1-10 1 p., 42563.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Activities
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Northumbria University - Undergraduate Open Day
Arends, D. (Participant)
4 Oct 2025Activity: Participating in or organising an event › Participating in a conference, workshop, ...
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Nature (Journal)
Arends, D. (Reviewer)
14 May 2025Activity: Publication peer-review and editorial work › Publication Peer-review
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Nature (Journal)
Arends, D. (Reviewer)
18 Aug 2024Activity: Publication peer-review and editorial work › Publication Peer-review
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