A case of transplacental transmission of Theileria equi in a foal in Trinidad

Karla Georges; Chuckwudozi Ezeokoli; Olivier Sparagano; Indira Pargass; Mervyn Campbell; Roger D’Abadie; Michael Yabsley

doi:10.1016/j.vetpar.2010.10.019

A case of transplacental transmission of Theileria equi in a foal in Trinidad

Karla Georges, Chuckwudozi Ezeokoli, Olivier Sparagano, Indira Pargass, Mervyn Campbell, Roger D’Abadie, Michael Yabsley

Northumbria University

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10 h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-GiemsaÂ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

Original language	English
Pages (from-to)	363-366
Journal	Veterinary Parasitology
Volume	175
Issue number	3-4
DOIs	https://doi.org/10.1016/j.vetpar.2010.10.019
Publication status	Published - 10 Feb 2011

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title = "A case of transplacental transmission of Theileria equi in a foal in Trinidad",

abstract = "Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10 h post-partum. A high parasitaemia (63\%) of piroplasms was observed in a Wright-Giemsa{\^A}{\textregistered} stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.",

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AU - Georges, Karla

AU - Ezeokoli, Chuckwudozi

AU - Sparagano, Olivier

AU - Pargass, Indira

AU - Campbell, Mervyn

AU - D’Abadie, Roger

AU - Yabsley, Michael

PY - 2011/2/10

Y1 - 2011/2/10

N2 - Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10 h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-GiemsaÂ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

AB - Equine piroplasmosis due to Theileria equi and Babesia caballi is endemic in Trinidad. A case of equine piroplasmosis due to T. equi was diagnosed in a thoroughbred foal at 10 h post-partum. A high parasitaemia (63%) of piroplasms was observed in a Wright-GiemsaÂ® stained thin blood smear from the foal. In addition, the 18S rRNA gene for Babesia/Theileria was amplified from DNA extracted from the blood of the foal and the mare. Amplified products were subjected to a reverse line blot hybridization assay (RLB), which confirmed the presence of T. equi DNA in the foal. The mare was negative by RLB but was positive for T. equi using a nested PCR and sequence analysis. In areas where equine piroplasmosis is endemic, severe jaundice in a post-partum foal may be easily misdiagnosed as neonatal isoerythrolysis. Foals with post-partum jaundice should be screened for equine piroplasmosis, which may be confirmed using molecular methods if available.

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DO - 10.1016/j.vetpar.2010.10.019

M3 - Article

SN - 0304-4017

VL - 175

SP - 363

EP - 366

JO - Veterinary Parasitology

JF - Veterinary Parasitology

IS - 3-4

ER -

A case of transplacental transmission of Theileria equi in a foal in Trinidad

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