A comparison between solid phase extraction and supercritical fluid extraction for the determination of fluconazole from animal feed

Sharmin Khundker, John Dean, Peter Jones

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

The application of supercritical fluid extraction with carbon dioxide and modified carbon dioxide for the determination of fluconazole from an animal feed was studied. A fractional factorial design approach was used to examine the significant experimental variables for quantitative extraction of fluconazole. Gas chromatography with either flame ionisation or mass selective detection was used for quantitation of the extracts. The results indicated that modifier (methanol) had the greatest effect on the recovery of fluconazole from the animal feed.
Original languageEnglish
Pages (from-to)1441-1447
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume13
Issue number12
DOIs
Publication statusPublished - Nov 1995

Fingerprint Dive into the research topics of 'A comparison between solid phase extraction and supercritical fluid extraction for the determination of fluconazole from animal feed'. Together they form a unique fingerprint.

Cite this