Abstract
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose, many natural, semi-synthetic and synthetic inhibitors have been developed by different screening methods to date. This review has focused on the tyrosinase inhibitors discovered from all sources and biochemically characterised in the last four decades.
| Original language | English |
|---|---|
| Pages (from-to) | 279-309 |
| Number of pages | 31 |
| Journal | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Volume | 34 |
| Issue number | 1 |
| Early online date | 3 Jan 2019 |
| DOIs | |
| Publication status | E-pub ahead of print - 3 Jan 2019 |
Keywords
- Tyrosinase
- Inhibitor
- Depigmentation agents
- Antibrowning compounds