Abstract
A novel molecular imprinting polymers (MIPs) based Mach-Zehnder interferometer (MZI) optical fiber sensor for detection of valsartan is designed and demonstrated experimentally. The MZI fiber sensor is made by a tapered microfiber structure with a taper diameter of 4.5 μm and a sensitivity of 1770 nm/RIU at the refective index of 1.33. The molecular imprinting polymers (MIPs) is synthesized using high-affinity binding sites via solid-phase based process, where valsartan is used as a target molecule. The sensor is treated utilizing a EDC/NHSS activated process and immobilized with the synthesized valsartan MIPs. Experimental results show that the developed MZI MIPs sensor has a linear response within the valsartan concentration range of 0 to 500 pg/mL, with a low detection limit of 35 pg/mL.
| Original language | English |
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| Title of host publication | 2024 14th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP) |
| Publisher | IEEE |
| Pages | 346-350 |
| Number of pages | 5 |
| ISBN (Electronic) | 9798350348743 |
| ISBN (Print) | 9798350348750 |
| DOIs | |
| Publication status | Published - 19 Jul 2024 |
| Event | 2024 14th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP) - Rome, Italy Duration: 17 Jul 2024 → 19 Jul 2024 Conference number: 14 |
Conference
| Conference | 2024 14th International Symposium on Communication Systems, Networks and Digital Signal Processing (CSNDSP) |
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| Abbreviated title | CSNDSP |
| Country/Territory | Italy |
| City | Rome |
| Period | 17/07/24 → 19/07/24 |
Keywords
- Optical fiber sensor
- Molecular imprinting polymers (MIPs)
- Mach Zehnder Interferometer (MZI)
- Biochemical sensing