A platform for experimental precision medicine: The extended BXD mouse family

David G. Ashbrook*, Danny Arends, Pjotr Prins, Megan K. Mulligan, Suheeta Roy, Evan G. Williams, Cathleen M. Lutz, Alicia Valenzuela, Casey J. Bohl, Jesse F. Ingels, Melinda S. McCarty, Arthur G. Centeno, Reinmar Hager, Johan Auwerx, Lu Lu, Robert W. Williams

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Ashbrook et al., have expanded the BXD family to 140 strains, providing a new tool for translational precision and predictive biology, and extended the usefulness of the deep phenome of >100 omics datasets and >7,500 classical phenotypes already available. They show increased precision and power by using new genotypes, updated models, and more strains.

Original languageEnglish
Pages (from-to)235-247.e9
Number of pages23
JournalCell Systems
Volume12
Issue number3
Early online date19 Jan 2021
DOIs
Publication statusPublished - 17 Mar 2021
Externally publishedYes

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