@article{49e4b0d39c544b86b54afe41cf7018ab,
title = "A platform for experimental precision medicine: The extended BXD mouse family",
abstract = "Ashbrook et al., have expanded the BXD family to 140 strains, providing a new tool for translational precision and predictive biology, and extended the usefulness of the deep phenome of >100 omics datasets and >7,500 classical phenotypes already available. They show increased precision and power by using new genotypes, updated models, and more strains.",
keywords = "complex trait, gene mapping, GXE, personalized medicine, power calculation, recombinant inbred strains, systems biology, systems genetics",
author = "Ashbrook, {David G.} and Danny Arends and Pjotr Prins and Mulligan, {Megan K.} and Suheeta Roy and Williams, {Evan G.} and Lutz, {Cathleen M.} and Alicia Valenzuela and Bohl, {Casey J.} and Ingels, {Jesse F.} and McCarty, {Melinda S.} and Centeno, {Arthur G.} and Reinmar Hager and Johan Auwerx and Lu Lu and Williams, {Robert W.}",
note = "Funding Information: We thank the support of the UT Center for Integrative and Translational Genomics and funds from the UT-ORNL Governor's Chair, NIDA grant P30DA044223 and NIAAA U01 AA013499 , U01 AA016662 , and U01 AA014425 for the work at UTHSC. Work in the Auwerx lab on the BXDs is supported by the {\'E}cole Polytechnique F{\'e}d{\'e}rale de Lausanne , the ERC ( AdG-787702 ), the SNSF ( 310030B-160318 ), the AgingX program of the Swiss Initiative for Systems Biology ( RTD 2013/153 ), and the NIH ( R01AG043930 ). The BXD Resource at the Jackson Laboratory is supported by NIH P40 OD011102 awarded to Dr. Cathleen M. Lutz. ",
year = "2021",
month = mar,
day = "17",
doi = "10.1016/j.cels.2020.12.002",
language = "English",
volume = "12",
pages = "235--247.e9",
journal = "Cell Systems",
issn = "2405-4712",
publisher = "Cell Press",
number = "3",
}