TY - JOUR
T1 - A prospective, longitudinal study of functional decline in individuals with Down's syndrome
AU - McKenzie, Karen
AU - Murray, George
AU - McKenzie, S.
AU - Muir, J.
PY - 1998/6
Y1 - 1998/6
N2 - This paper used the standardized criteria proposed by Aylward et al I995 for diagnosing Alzheimer's Disease in individuals with learning disabilities to undertake a prospective, longitudinal study of 22 individuals with Down's syndrome. Results show that, after a period of up to 6 years, four individuals showed functional decline. A similar pattern of decline was found to that described in previous studies, although the mean age of onset was later. All four subjects met the criteria for probable Alzheimer's Disease.
AB - This paper used the standardized criteria proposed by Aylward et al I995 for diagnosing Alzheimer's Disease in individuals with learning disabilities to undertake a prospective, longitudinal study of 22 individuals with Down's syndrome. Results show that, after a period of up to 6 years, four individuals showed functional decline. A similar pattern of decline was found to that described in previous studies, although the mean age of onset was later. All four subjects met the criteria for probable Alzheimer's Disease.
U2 - 10.1177/146900479800200207
DO - 10.1177/146900479800200207
M3 - Article
SN - 1744-6295
VL - 2
SP - 98
EP - 104
JO - Journal of Intellectual Disabilities
JF - Journal of Intellectual Disabilities
IS - 2
ER -