A steroid-based cryptand for halide anions

Anthony P. Davis*, John F. Gilmer, Justin J. Perry

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

95 Citations (Scopus)


As a neutral, lipophilic, purely organic host, the macrocycle 1 may deservedly be labeled an “anion-binding counterpart” of a crown ether or cryptand. Macrocycle 1 was synthesized from the inexpensive steroid cholic acid. It forms 1:1 complexes with fluoride, chloride, and bromide and shows good discrimination in favor of the smaller anions. R = pentyl.
Original languageEnglish
Pages (from-to)1312-1315
Number of pages4
JournalAngewandte Chemie (International Edition in English)
Issue number12
Publication statusPublished - 9 Jul 1996
Externally publishedYes


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