A tunable morphing polyelectrolyte system for smart ocular applications

Ansu Sun; Sreepathy Sridhar; Sherry Chen; Yifan Li; Ben Bin Xu

doi:10.1109/Transducers50396.2021.9495587

A tunable morphing polyelectrolyte system for smart ocular applications

Ansu Sun, Sreepathy Sridhar, Sherry Chen, Yifan Li^*, Ben Bin Xu^*

^*Corresponding author for this work

Mechanical and Construction Engineering Department

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

65 Downloads (Pure)

Abstract

For the first time, a focal-length tunable intra-ocular lens (IOL) device has been realized by a standard-shaped, homogeneous “one material” system. Different to existing technologies, this poly(N-isopropylacrylamide) gel (PNIPAM) based polyelectrolyte system doesn’t require any additional materials (e.g. metal electrodes, movable mechanical structures) to achieve a controllable lens shape transformation for the focal-length shifting actuation. The designed morphological deformation mechanism employs ionic-strength responsive mechanical buckling via controlled swelling of PNIPAM in phosphate buffered saline (PBS) with similar concentration to human eye liquid. This unique approach will unlock great potential in a wide range of smart ocular applications.

Original language	English
Title of host publication	21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021
Place of Publication	Piscataway, NJ
Publisher	IEEE
Pages	1464-1467
Number of pages	4
ISBN (Electronic)	9781665412674
ISBN (Print)	9781665448451
DOIs	https://doi.org/10.1109/Transducers50396.2021.9495587
Publication status	Published - 20 Jun 2021
Event	Transducers 2021: The 21st International conference on Solid-state sensors, actuators and microsystems - Online Duration: 20 Jun 2021 → 25 Jun 2021 https://www.transducers2021.org/

Conference

Conference	Transducers 2021
Abbreviated title	Transducers 2021
Period	20/06/21 → 25/06/21
Internet address	https://www.transducers2021.org/

Keywords

PNIPAM
PNIPAAm
responsive polymer
intraocular Lens
focal length
swelling

Access to Document

10.1109/Transducers50396.2021.9495587

0427Accepted author manuscript, 662 KB

Cite this

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title = "A tunable morphing polyelectrolyte system for smart ocular applications",

abstract = "For the first time, a focal-length tunable intra-ocular lens (IOL) device has been realized by a standard-shaped, homogeneous “one material” system. Different to existing technologies, this poly(N-isopropylacrylamide) gel (PNIPAM) based polyelectrolyte system doesn{\textquoteright}t require any additional materials (e.g. metal electrodes, movable mechanical structures) to achieve a controllable lens shape transformation for the focal-length shifting actuation. The designed morphological deformation mechanism employs ionic-strength responsive mechanical buckling via controlled swelling of PNIPAM in phosphate buffered saline (PBS) with similar concentration to human eye liquid. This unique approach will unlock great potential in a wide range of smart ocular applications.",

keywords = "PNIPAM, PNIPAAm, responsive polymer, intraocular Lens, focal length, swelling",

author = "Ansu Sun and Sreepathy Sridhar and Sherry Chen and Yifan Li and Xu, {Ben Bin}",

note = "This work was supported by EPSRC UK Fluid Network (grant no. EP/N032861, https://fluids.ac.uk/). The authors would also like to acknowledge other support from the EPSRC (grant Nos. EP/N007921 and EP/L026899). Data associated with this article are available via Northumbria Research Data Management scheme.; Transducers 2021 : The 21st International conference on Solid-state sensors, actuators and microsystems, Transducers 2021 ; Conference date: 20-06-2021 Through 25-06-2021",

year = "2021",

month = jun,

day = "20",

doi = "10.1109/Transducers50396.2021.9495587",

language = "English",

isbn = "9781665448451",

pages = "1464--1467",

booktitle = "21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021",

publisher = "IEEE",

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url = "https://www.transducers2021.org/",

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A tunable morphing polyelectrolyte system for smart ocular applications. / Sun, Ansu; Sridhar, Sreepathy; Chen, Sherry et al.
21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021. Piscataway, NJ: IEEE, 2021. p. 1464-1467 B5-550l.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - A tunable morphing polyelectrolyte system for smart ocular applications

AU - Sun, Ansu

AU - Sridhar, Sreepathy

AU - Chen, Sherry

AU - Li, Yifan

AU - Xu, Ben Bin

N1 - This work was supported by EPSRC UK Fluid Network (grant no. EP/N032861, https://fluids.ac.uk/). The authors would also like to acknowledge other support from the EPSRC (grant Nos. EP/N007921 and EP/L026899). Data associated with this article are available via Northumbria Research Data Management scheme.

PY - 2021/6/20

Y1 - 2021/6/20

N2 - For the first time, a focal-length tunable intra-ocular lens (IOL) device has been realized by a standard-shaped, homogeneous “one material” system. Different to existing technologies, this poly(N-isopropylacrylamide) gel (PNIPAM) based polyelectrolyte system doesn’t require any additional materials (e.g. metal electrodes, movable mechanical structures) to achieve a controllable lens shape transformation for the focal-length shifting actuation. The designed morphological deformation mechanism employs ionic-strength responsive mechanical buckling via controlled swelling of PNIPAM in phosphate buffered saline (PBS) with similar concentration to human eye liquid. This unique approach will unlock great potential in a wide range of smart ocular applications.

AB - For the first time, a focal-length tunable intra-ocular lens (IOL) device has been realized by a standard-shaped, homogeneous “one material” system. Different to existing technologies, this poly(N-isopropylacrylamide) gel (PNIPAM) based polyelectrolyte system doesn’t require any additional materials (e.g. metal electrodes, movable mechanical structures) to achieve a controllable lens shape transformation for the focal-length shifting actuation. The designed morphological deformation mechanism employs ionic-strength responsive mechanical buckling via controlled swelling of PNIPAM in phosphate buffered saline (PBS) with similar concentration to human eye liquid. This unique approach will unlock great potential in a wide range of smart ocular applications.

KW - PNIPAM

KW - PNIPAAm

KW - responsive polymer

KW - intraocular Lens

KW - focal length

KW - swelling

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DO - 10.1109/Transducers50396.2021.9495587

M3 - Conference contribution

SN - 9781665448451

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BT - 21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021

PB - IEEE

CY - Piscataway, NJ

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ER -

A tunable morphing polyelectrolyte system for smart ocular applications

Abstract

Conference

Keywords

Access to Document

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Fingerprint

Stimuli-responsive gel based microfluidic switch

Cite this

A tunable morphing polyelectrolyte system for smart ocular applications

Abstract

Conference

Keywords

Access to Document

Other files and links

Fingerprint

Projects

Stimuli-responsive gel based microfluidic switch

Cite this