An efficient synthesis of azetidines with (2-bromoethyl)sulfonium triflate

Sven P. Fritz; Juan F. Moya; Matthew G. Unthank; Eoghan M. Mcgarrigle; Varinder K. Aggarwal

doi:10.1055/s-0031-1290951

An efficient synthesis of azetidines with (2-bromoethyl)sulfonium triflate

Sven P. Fritz, Juan F. Moya, Matthew G. Unthank, Eoghan M. Mcgarrigle^*, Varinder K. Aggarwal

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.

Original language	English
Pages (from-to)	1584-1590
Number of pages	7
Journal	Synthesis
Volume	44
Issue number	10
DOIs	https://doi.org/10.1055/s-0031-1290951
Publication status	Published - 26 Apr 2012
Externally published	Yes

Keywords

annulations
cyclizations
heterocycles
sulfur
ylides

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10.1055/s-0031-1290951

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abstract = "Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.",

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AU - Fritz, Sven P.

AU - Moya, Juan F.

AU - Unthank, Matthew G.

AU - Mcgarrigle, Eoghan M.

AU - Aggarwal, Varinder K.

PY - 2012/4/26

Y1 - 2012/4/26

N2 - Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.

AB - Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.

KW - annulations

KW - cyclizations

KW - heterocycles

KW - sulfur

KW - ylides

UR - https://www.scopus.com/pages/publications/84860164329

U2 - 10.1055/s-0031-1290951

DO - 10.1055/s-0031-1290951

M3 - Article

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SN - 0039-7881

VL - 44

SP - 1584

EP - 1590

JO - Synthesis

JF - Synthesis

IS - 10

ER -

An efficient synthesis of azetidines with (2-bromoethyl)sulfonium triflate

Abstract

Keywords

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