An improved synthesis of 10-isobornylsultone

Frank Lewis, David Grayson

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)
    35 Downloads (Pure)

    Abstract

    A modified and improved synthesis of 10-isobornylsultone in three steps and in 81% overall yield starting from (+)-camphor-10-sulfonic acid is described. The synthesis proceeds via methyl sulfonate ester formation, stereoselective reduction and base-catalysed intramolecular cyclisation.
    Original languageEnglish
    Pages (from-to)1150-1152
    JournalTetrahedron Asymmetry
    Volume25
    Issue number15
    DOIs
    Publication statusPublished - 15 Aug 2014

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