Antimicrobial activity of C. intybus leaves extract in different solvent systems: a green approach for sustainable biomedicine

Antimicrobial resistance (AMR) is global public health concern which is one of the reasons for synthesis of antimicrobial compounds. The antibacterial activity of Cichorium intybus leaf extracts was studied against a set of three bacteria, i.e. Escherichia coli, Staphylococcus aureus and Pasturella multocida pathogenic bacteria, and also the antifungal activity was determined against Aspergillus flavus and Aspergillus paraciticus. According to the current study, C. intybus leaf extracts have antibacterial activity, which can have many positive effects and might be used as a natural source of antibacterial agents. Similarly, antifungal activity was determined against Aspergillus flavus and Aspergillus paraciticus. 80% methanol showed a minimum MIC that is 51 µg/ml with maximum antifungal activity. Mineral analysis evaluated the presence of microelements in order Ca > Mg > Na. 80% Methanolic leaf extract of C. intybus showed maximum anti-microbial activity. This presents promising potential for use as biomedicine, which needs further studies in the lab and beyond.