Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients

Bruno Remigio Cavalcante; Antonio H Germano-Soares; Aline M Gerage; Anthony Leicht; Rafael M Tassitano; Henrique Bortolotti; Fábio Gazelato de Mello Franco; Nelson Wolosker; Gabriel G Cucato; Raphael M Ritti-Dias

doi:10.1016/j.ejvs.2018.02.010

Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients

Bruno Remigio Cavalcante, Antonio H Germano-Soares, Aline M Gerage, Anthony Leicht, Rafael M Tassitano, Henrique Bortolotti, Fábio Gazelato de Mello Franco, Nelson Wolosker, Gabriel G Cucato, Raphael M Ritti-Dias

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

OBJECTIVE: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease.

METHODS: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function.

RESULTS: Positive and significant associations were observed between moderate to vigorous physical activity (p = .039) and walking capacity (p = .030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome.

CONCLUSION: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.

Original language	English
Pages (from-to)	672-678
Number of pages	7
Journal	European Journal of Vascular and Endovascular Surgery
Volume	55
Issue number	5
Early online date	23 Mar 2018
DOIs	https://doi.org/10.1016/j.ejvs.2018.02.010
Publication status	Published - 1 May 2018
Externally published	Yes

Keywords

Aged
Cognition/physiology
Cross-Sectional Studies
Echocardiography, Doppler, Color/methods
Executive Function/physiology
Exercise/psychology
Exercise Tolerance
Female
Humans
Intelligence Tests
Male
Middle Aged
Peripheral Arterial Disease/diagnosis
Physical Fitness/physiology
Statistics as Topic
Walk Test/methods
Walking/psychology

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10.1016/j.ejvs.2018.02.010Licence: Other

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Cavalcante, B. R., Germano-Soares, A. H., Gerage, A. M., Leicht, A., Tassitano, R. M., Bortolotti, H., de Mello Franco, F. G., Wolosker, N., Cucato, G. G., & Ritti-Dias, R. M. (2018). Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients. European Journal of Vascular and Endovascular Surgery, 55(5), 672-678. https://doi.org/10.1016/j.ejvs.2018.02.010

@article{6f0fd659d96b48f3947c638de7ec0237,

title = "Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients",

abstract = "OBJECTIVE: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease.METHODS: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function.RESULTS: Positive and significant associations were observed between moderate to vigorous physical activity (p = .039) and walking capacity (p = .030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome.CONCLUSION: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.",

keywords = "Aged, Cognition/physiology, Cross-Sectional Studies, Echocardiography, Doppler, Color/methods, Executive Function/physiology, Exercise/psychology, Exercise Tolerance, Female, Humans, Intelligence Tests, Male, Middle Aged, Peripheral Arterial Disease/diagnosis, Physical Fitness/physiology, Statistics as Topic, Walk Test/methods, Walking/psychology",

author = "Cavalcante, {Bruno Remigio} and Germano-Soares, {Antonio H} and Gerage, {Aline M} and Anthony Leicht and Tassitano, {Rafael M} and Henrique Bortolotti and {de Mello Franco}, {F{\'a}bio Gazelato} and Nelson Wolosker and Cucato, {Gabriel G} and Ritti-Dias, {Raphael M}",

year = "2018",

month = may,

day = "1",

doi = "10.1016/j.ejvs.2018.02.010",

language = "English",

volume = "55",

pages = "672--678",

journal = "European Journal of Vascular and Endovascular Surgery",

issn = "1078-5884",

publisher = "W.B. Saunders",

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Cavalcante, BR, Germano-Soares, AH, Gerage, AM, Leicht, A, Tassitano, RM, Bortolotti, H, de Mello Franco, FG, Wolosker, N, Cucato, GG & Ritti-Dias, RM 2018, 'Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients', European Journal of Vascular and Endovascular Surgery, vol. 55, no. 5, pp. 672-678. https://doi.org/10.1016/j.ejvs.2018.02.010

TY - JOUR

T1 - Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients

AU - Cavalcante, Bruno Remigio

AU - Germano-Soares, Antonio H

AU - Gerage, Aline M

AU - Leicht, Anthony

AU - Tassitano, Rafael M

AU - Bortolotti, Henrique

AU - de Mello Franco, Fábio Gazelato

AU - Wolosker, Nelson

AU - Cucato, Gabriel G

AU - Ritti-Dias, Raphael M

PY - 2018/5/1

Y1 - 2018/5/1

N2 - OBJECTIVE: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease.METHODS: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function.RESULTS: Positive and significant associations were observed between moderate to vigorous physical activity (p = .039) and walking capacity (p = .030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome.CONCLUSION: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.

AB - OBJECTIVE: To identify the association between objectively measured physical activity and walking capacity with cognitive function in patients with symptomatic peripheral artery disease.METHODS: This was an observational, cross sectional study. One hundred and thirty patients (age 67 ± 8 years) were recruited at a tertiary centre specializing in vascular disease. Cognitive function (global, memory, executive function and attention) was evaluated using the Montreal Cognitive Assessment tool. Physical activity levels (total, light, and moderate-vigorous) were obtained using an accelerometer. A 6 min and 4 m walk test were undertaken to assess walking capacity. Crude and covariate adjusted, linear regression analyses confirmed significant associations between physical activity levels and walking capacity with cognitive function.RESULTS: Positive and significant associations were observed between moderate to vigorous physical activity (p = .039) and walking capacity (p = .030) with memory after adjusting for covariates. No significant association was identified between light physical activity and usual gait speed with any cognitive function outcome.CONCLUSION: Greater memory performance was associated with greater moderate to vigorous physical activity levels and walking capacity in patients with symptomatic peripheral artery disease. Clinical interventions focused on improving moderate to vigorous physical activity levels and walking capacity may provide important therapies to potentially enhance cognitive health in patients with peripheral artery disease.

KW - Aged

KW - Cognition/physiology

KW - Cross-Sectional Studies

KW - Echocardiography, Doppler, Color/methods

KW - Executive Function/physiology

KW - Exercise/psychology

KW - Exercise Tolerance

KW - Female

KW - Humans

KW - Intelligence Tests

KW - Male

KW - Middle Aged

KW - Peripheral Arterial Disease/diagnosis

KW - Physical Fitness/physiology

KW - Statistics as Topic

KW - Walk Test/methods

KW - Walking/psychology

U2 - 10.1016/j.ejvs.2018.02.010

DO - 10.1016/j.ejvs.2018.02.010

M3 - Article

C2 - 29580833

SN - 1078-5884

VL - 55

SP - 672

EP - 678

JO - European Journal of Vascular and Endovascular Surgery

JF - European Journal of Vascular and Endovascular Surgery

IS - 5

ER -

Association between physical activity and walking capacity with cognitive function in peripheral artery disease patients

Abstract

Keywords

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