Atomic force microscope integrated with a multiple degrees-of-freedom magnetic actuator

Hamdi Torun (Inventor), Olgac Ergeneman (Inventor), Salvador Pane (Inventor), Bradley Nelson (Inventor)

Research output: Patent

Abstract

The present invention relates to a biomolecular measurement system (1), which enables to measure the intermolecular forces arising from the interaction between two biomolecules or the intramolecular forces within a single biomolecule by using an atomic force microscope (AFM). In the present invention, the cantilever (2) is moved only when the actuator (4) moves the magnetic nanowire (3) and thus moves the molecule attached to the end of the magnetic nanowire (3). Since the cantilever (2) is not moved, fluctuation and disturbance is not created in the liquid containing the biomolecules. Thus, the measurements are made more accurately and with higher resolution. Additionally, by means of the actuator (4), the biomolecules are enabled to be moved upon exertion of magnetic force at any coordinate on x, y and z axes on the nanowire (3), or exertion of torque on two axes.
Original languageEnglish
Patent numberUS2016266107 (A1)
IPCUSPTO
Priority date15/08/14
Publication statusPublished - 9 May 2017
Externally publishedYes

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