Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility

Jiajun Qiu, Tingting Yang, Yifan Li, Wenhao Qian*, Xuanyong Liu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Although titanium and its alloys are extensively used in orthopedics and dentistry fields, implant failures still happen because of implant-associated infections. Herein, Au@Ag@Pt core-shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface and the antibacterial activity and biocompatibility were investigated. The results showed that antibacterial rates of Ti-Au@Ag@Pt against S. epidermidis and P. aeruginosa were 89.7% and 92.7%, respectively. Besides, Ti-Au@Ag@Pt showed no obvious cell toxicity with MC3T3-E1 cells grew well on the sample surface. It was discovered that the Pt shell layer on Ti-Au@Ag@Pt slowed down the Ag ion release rate which endowed medical titanium surface with both antibacterial activity and good biocompatibility.
Original languageEnglish
JournalRare Metals
Early online date19 Aug 2021
DOIs
Publication statusE-pub ahead of print - 19 Aug 2021

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