Abstract
Although titanium and its alloys are extensively used in orthopedics and dentistry fields, implant failures still happen because of implant-associated infections. Herein, Au@Ag@Pt core-shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface and the antibacterial activity and biocompatibility were investigated. The results showed that antibacterial rates of Ti-Au@Ag@Pt against S. epidermidis and P. aeruginosa were 89.7% and 92.7%, respectively. Besides, Ti-Au@Ag@Pt showed no obvious cell toxicity with MC3T3-E1 cells grew well on the sample surface. It was discovered that the Pt shell layer on Ti-Au@Ag@Pt slowed down the Ag ion release rate which endowed medical titanium surface with both antibacterial activity and good biocompatibility.
Original language | English |
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Pages (from-to) | 630-638 |
Number of pages | 9 |
Journal | Rare Metals |
Volume | 41 |
Issue number | 2 |
Early online date | 19 Aug 2021 |
DOIs | |
Publication status | Published - 1 Feb 2022 |
Keywords
- titanium
- silver
- nanorod
- antibacterial
- biocompatibility