Bacterial computing with engineered populations

Martyn Amos, Ilka Maria Axmann, Nils Bluethgen, Fernando de la Cruz, Alfonso Jaramillo, Alfonso Rodriguez-Paton, Friedrich Simmel

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)
51 Downloads (Pure)

Abstract

We describe strategies for the construction of bacterial computing platforms by describing a number of results from the recently completed bacterial computing with engineered populations project. In general, the implementation of such systems requires a framework containing various components such as intracellular circuits, single cell input/output and cell–cell interfacing, as well as extensive analysis. In this overview paper, we describe our approach to each of these, and suggest possible areas for future research.
Original languageEnglish
Article number2014.0218
JournalPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume373
Issue number2046
DOIs
Publication statusPublished - 28 Jul 2015

Keywords

  • synthetic biology
  • unconventional computing
  • conjugation
  • simulation
  • mathematical modelling

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