TY - JOUR
T1 - Black bone MRI morphometry for mandibular cortical bone measurement in head and neck cancer patients: Prospective method comparison with CT
AU - Joint Head and Neck MRI-Radiotherapy Development Cooperative
AU - van Dijk, Lisanne V.
AU - Ventura, Juan
AU - Wahid, Kareem
AU - Zhu, Lin L.
AU - McDonald, Brigid A.
AU - Ahmed, Sara
AU - Sanders, Keith
AU - Stieb, Sonja M.
AU - McCoy, Lance
AU - Sharafi, Christina S.
AU - Preston, Kathryn E.
AU - West, Natalie A.
AU - Mirbahaeddin, Sarah
AU - El-Habashy, Dina M.
AU - Salzillo, Travis
AU - Mulder, Samuel
AU - Fahim, Joly
AU - DeArmas, Aubryane
AU - Arbab, Mona
AU - Ding, Yao
AU - Wang, Jihong
AU - Rigaud, Bastien
AU - Sen, Anando
AU - Chambers, Mark
AU - Hutcheson, Katherine A.
AU - Brock, Kristy K.
AU - Mohamed, Abdallah S.R.
AU - Lai, Stephen Y.
AU - Fuller, Clifton D.
PY - 2025/12/29
Y1 - 2025/12/29
N2 - Objectives : Determine the utility of low-flip angle “black bone” magnetic resonance imaging (MRI) for cortical mandibular bone assessment compared to computed tomography (CT). Methods : Quantification of cortical mandibular bone width was performed per Hamada et al. at 15 cross-sectional interdentium locations on pre-treatment black bone MRI and CT for 15 oropharyngeal cancer patients, with inter-observer analyses on a subset of 3 patients by 11 observers. CT and MRI measurements were compared using Bland-Altman analysis, Lin’s concordance, and Deming regression; inter-observer variability was assessed with absolute variance and intraclass correlation coefficient (ICC). Results : Bland Altman and Deming regression analyses showed CT and black bone MRI measurements were comparable within ±0.85mm limits of agreement, and systematically smaller for MRI. ICC (0.60[0.52;0.67]) showed moderate equivalence between modalities. The average absolute variance between the observers was similar on CT (1.13±0.06mm) and MRI (1.15±0.06mm). ICC analysis showed that measurement consistency was significantly higher (p
AB - Objectives : Determine the utility of low-flip angle “black bone” magnetic resonance imaging (MRI) for cortical mandibular bone assessment compared to computed tomography (CT). Methods : Quantification of cortical mandibular bone width was performed per Hamada et al. at 15 cross-sectional interdentium locations on pre-treatment black bone MRI and CT for 15 oropharyngeal cancer patients, with inter-observer analyses on a subset of 3 patients by 11 observers. CT and MRI measurements were compared using Bland-Altman analysis, Lin’s concordance, and Deming regression; inter-observer variability was assessed with absolute variance and intraclass correlation coefficient (ICC). Results : Bland Altman and Deming regression analyses showed CT and black bone MRI measurements were comparable within ±0.85mm limits of agreement, and systematically smaller for MRI. ICC (0.60[0.52;0.67]) showed moderate equivalence between modalities. The average absolute variance between the observers was similar on CT (1.13±0.06mm) and MRI (1.15±0.06mm). ICC analysis showed that measurement consistency was significantly higher (p
U2 - 10.1016/j.oooo.2025.12.013
DO - 10.1016/j.oooo.2025.12.013
M3 - Article
SN - 2212-4403
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
ER -
