British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Elizabeth J. Price; Stuart Benjamin; Michele Bombardieri; Simon Bowman; Sara  Carty; Coziana Ciurtin; Bridget Crampton; Annabel Dawson; Benjamin A. Fisher; Ian Giles; Peter Glennon; Monica Gupta; Katie Hackett; Genevieve Larkin; Wan-Fai Ng; A.V. Ramanan; Saad Rassam; Saaeha Rauz; Smith Guy; Nurhan Sutcliffe; Anwar R. Tappuni; Stephen B. Walsh

doi:10.1093/rheumatology/keae152

British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Elizabeth J. Price^*, Stuart Benjamin, Michele Bombardieri, Simon Bowman, Sara Carty, Coziana Ciurtin, Bridget Crampton, Annabel Dawson, Benjamin A. Fisher, Ian Giles, Peter Glennon, Monica Gupta, Katie Hackett, Genevieve Larkin, Wan-Fai Ng, A.V. Ramanan, Saad Rassam, Saaeha Rauz, Smith Guy, Nurhan SutcliffeAnwar R. Tappuni, Stephen B. Walsh

^*Corresponding author for this work

Social Work, Education & Community Wellbeing

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Abstract

Sjögren disease (SD) is a chronic, autoimmune disease of unknown aetiology with significant impact on quality of life. Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations are common. The key management aim should be to empower the individual to manage their condition—conserving, replacing and stimulating secretions; and preventing damage and suppressing systemic disease activity. This guideline builds on and widens the recommendations developed for the first guideline published in 2017. We have included advice on the management of children and adolescents where appropriate to provide a comprehensive guideline for UK-based rheumatology teams.

Original language	English
Article number	keae152
Pages (from-to)	409-439
Number of pages	31
Journal	Rheumatology
Volume	64
Issue number	2
Early online date	16 Apr 2024
DOIs	https://doi.org/10.1093/rheumatology/keae152
Publication status	Published - 1 Feb 2025

Keywords

Sjogren
sicca
treatment
management
guideline
recommendation
juvenile onset
adult onset
Sjögren's syndrome
Sjögren disease
recommendations
connective tissue disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Sjogren_s_guideline_2023_full_guideline_FINAL_revised_Feb_2024_CLEAN_002_Accepted author manuscript, 606 KBLicence: CC BY
keae152Final published version, 3.06 MBLicence: CC BY

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Price, E. J., Benjamin, S., Bombardieri, M., Bowman, S., Carty, S., Ciurtin, C., Crampton, B., Dawson, A., Fisher, B. A., Giles, I., Glennon, P., Gupta, M., Hackett, K., Larkin, G., Ng, W.-F., Ramanan, A. V., Rassam, S., Rauz, S., Guy, S., ... Walsh, S. B. (2025). British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease. Rheumatology, 64(2), 409-439. Article keae152. https://doi.org/10.1093/rheumatology/keae152

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title = "British Society for Rheumatology guideline on management of adult and juvenile onset Sj{\"o}gren disease",

abstract = "Sj{\"o}gren disease (SD) is a chronic, autoimmune disease of unknown aetiology with significant impact on quality of life. Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations are common. The key management aim should be to empower the individual to manage their condition—conserving, replacing and stimulating secretions; and preventing damage and suppressing systemic disease activity. This guideline builds on and widens the recommendations developed for the first guideline published in 2017. We have included advice on the management of children and adolescents where appropriate to provide a comprehensive guideline for UK-based rheumatology teams.",

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author = "Price, {Elizabeth J.} and Stuart Benjamin and Michele Bombardieri and Simon Bowman and Sara Carty and Coziana Ciurtin and Bridget Crampton and Annabel Dawson and Fisher, {Benjamin A.} and Ian Giles and Peter Glennon and Monica Gupta and Katie Hackett and Genevieve Larkin and Wan-Fai Ng and A.V. Ramanan and Saad Rassam and Saaeha Rauz and Smith Guy and Nurhan Sutcliffe and Tappuni, {Anwar R.} and Walsh, {Stephen B.}",

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doi = "10.1093/rheumatology/keae152",

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Price, EJ, Benjamin, S, Bombardieri, M, Bowman, S, Carty, S, Ciurtin, C, Crampton, B, Dawson, A, Fisher, BA, Giles, I, Glennon, P, Gupta, M, Hackett, K, Larkin, G, Ng, W-F, Ramanan, AV, Rassam, S, Rauz, S, Guy, S, Sutcliffe, N, Tappuni, AR & Walsh, SB 2025, 'British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease', Rheumatology, vol. 64, no. 2, keae152, pp. 409-439. https://doi.org/10.1093/rheumatology/keae152

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AU - Price, Elizabeth J.

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AU - Bombardieri, Michele

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AU - Carty, Sara

AU - Ciurtin, Coziana

AU - Crampton, Bridget

AU - Dawson, Annabel

AU - Fisher, Benjamin A.

AU - Giles, Ian

AU - Glennon, Peter

AU - Gupta, Monica

AU - Hackett, Katie

AU - Larkin, Genevieve

AU - Ng, Wan-Fai

AU - Ramanan, A.V.

AU - Rassam, Saad

AU - Rauz, Saaeha

AU - Guy, Smith

AU - Sutcliffe, Nurhan

AU - Tappuni, Anwar R.

AU - Walsh, Stephen B.

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AB - Sjögren disease (SD) is a chronic, autoimmune disease of unknown aetiology with significant impact on quality of life. Although dryness (sicca) of the eyes and mouth are the classically described features, dryness of other mucosal surfaces and systemic manifestations are common. The key management aim should be to empower the individual to manage their condition—conserving, replacing and stimulating secretions; and preventing damage and suppressing systemic disease activity. This guideline builds on and widens the recommendations developed for the first guideline published in 2017. We have included advice on the management of children and adolescents where appropriate to provide a comprehensive guideline for UK-based rheumatology teams.

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KW - management

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KW - recommendation

KW - juvenile onset

KW - adult onset

KW - Sjögren's syndrome

KW - Sjögren disease

KW - recommendations

KW - connective tissue disease

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JF - Rheumatology

IS - 2

M1 - keae152

ER -

British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Abstract

Keywords

UN SDGs

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Executive summary: British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Cite this