Changes in the substance P-containing innervation of the lumbosacral spinal cord in male Wistar rats as a consequence of ageing

Richard Ranson, David Priestley, Robert Santer, Alan Watson

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Substance P is implicated in controlling micturition reflexes. This investigation revealed Substance P immunoreactive terminals which markedly declined in spinal regions associated with bladder emptying/storage that were not replicated in regions associated with sphincter control. This observation reinforces concepts of ‘differential susceptibility’ to ageing in terms of axon pathology.
Original languageEnglish
Pages (from-to)139-144
JournalBrain Research
Volume1036
Issue number1-2
DOIs
Publication statusPublished - Mar 2005

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