Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing

Laura C. Greaves, Marco Nooteboom, Joanna L. Elson, Helen A. L. Tuppen, Geoffrey A. Taylor, Daniel M. Commane, Ramesh P. Arasaradnam, Konstantin Khrapko, Robert W. Taylor, Thomas B. L. Kirkwood, John C. Mathers, Douglass M. Turnbull

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Biochemistry, Genetics and Molecular Biology