Common Carotid Artery Diameter, Blood Flow Velocity and Wave Intensity Responses at Rest and during Exercise in Young Healthy Humans: A Reproducibility Study

Nicola Pomella, Eurico Nestor Wilhelm, Christina Kolyva, José González-Alonso, Mark Rakobowchuk, Ashraf W Khir

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)
11 Downloads (Pure)

Abstract

The aim of this study was to assess the reproducibility of non-invasive, ultrasound-derived wave intensity (WI) in humans at the common carotid artery. Common carotid artery diameter and blood velocity of 12 healthy young participants were recorded at rest and during mild cycling, to assess peak diameter, change in diameter, peak velocity, change in velocity, time derivatives, non-invasive wave speed and WI. Diameter, velocity and WI parameters were fairly reproducible. Diameter variables exhibited higher reproducibility than corresponding velocity variables (intra-class correlation coefficient [ICC] = 0.79 vs. 0.73) and lower dispersion (coefficient of variation [CV] = 5% vs. 9%). Wave speed had fair reproducibility (ICC = 0.6, CV = 16%). WI energy variables exhibited higher reproducibility than corresponding peaks (ICC = 0.78 vs. 0.74) and lower dispersion (CV = 16% vs. 18%). The majority of variables had higher ICCs and lower CVs during exercise. We conclude that non-invasive WI analysis is reliable both at rest and during exercise.

Original languageEnglish
Pages (from-to)943-957
Number of pages15
JournalUltrasound in Medicine and Biology
Volume43
Issue number5
Early online date23 Feb 2017
DOIs
Publication statusPublished - 1 May 2017
Externally publishedYes

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