Abstract
We performed an observational study on 137 patients undergoing carotid endarterectomy (CEA). Patients on statins were less likely to have had symptoms in the 4 weeks before CEA (p = 0.0049) and were less likely to have spontaneous cerebral embolization detected by transcranial Doppler (p = 0.0459). Carotid plaques retrieved at CEA from patients taking statins revealed significantly lower concentrations of matrix metalloproteinase-1 (p = 0.0176), matrix metalloproteinase-9 (p = 0.0018), and interleukin-6 (p = 0.0005).
Original language | English |
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Pages (from-to) | 144-146 |
Number of pages | 3 |
Journal | American Journal of Cardiology |
Volume | 94 |
Issue number | 1 |
Early online date | 23 Jun 2004 |
DOIs | |
Publication status | Published - 1 Jul 2004 |
Externally published | Yes |