Corynephages: Infections of the Infectors

Vartul Sangal, Paul Hoskisson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

17 Citations (Scopus)

Abstract

Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.
Original languageEnglish
Title of host publicationCorynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications
EditorsAndreas Burkovski
Place of PublicationLondon
PublisherSpringer
Pages67-81
ISBN (Print)978-9400776234
DOIs
Publication statusPublished - 1 Jan 2014

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