Corynephages: Infections of the Infectors

Vartul Sangal; Paul Hoskisson

doi:10.1007/978-94-007-7624-1

Corynephages: Infections of the Infectors

Vartul Sangal, Paul Hoskisson

Applied Sciences Department

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

25 Citations (Scopus)

Abstract

Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.

Original language	English
Title of host publication	Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications
Editors	Andreas Burkovski
Place of Publication	London
Publisher	Springer
Pages	67-81
ISBN (Print)	978-9400776234
DOIs	https://doi.org/10.1007/978-94-007-7624-1
Publication status	Published - 1 Jan 2014

Keywords

bacteriophage
toxin

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10.1007/978-94-007-7624-1

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AB - Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.

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KW - toxin

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DO - 10.1007/978-94-007-7624-1

M3 - Chapter

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PB - Springer

CY - London

ER -

Corynephages: Infections of the Infectors

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Keywords

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