Degradation of halogenated aliphatic compounds: The role of adaptation

F. Pries; J. R. van der Ploeg; J. Dolfing; D. B. Janssen

doi:10.1111/j.1574-6976.1994.tb00140.x

Degradation of halogenated aliphatic compounds: The role of adaptation

F. Pries, J. R. van der Ploeg, J. Dolfing, D. B. Janssen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.

Original language	English
Pages (from-to)	279-295
Number of pages	17
Journal	FEMS Microbiology Reviews
Volume	15
Issue number	2-3
DOIs	https://doi.org/10.1111/j.1574-6976.1994.tb00140.x
Publication status	Published - 1 Oct 1994
Externally published	Yes

Keywords

1,2-Dichloroethane
Adaptation
Chloroacetate
Dehalogenase
Evolution
Trichloroethylene

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1574-6976.1994.tb00140.x

Cite this

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title = "Degradation of halogenated aliphatic compounds: The role of adaptation",

abstract = "A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.",

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T1 - Degradation of halogenated aliphatic compounds

T2 - The role of adaptation

AU - Pries, F.

AU - van der Ploeg, J. R.

AU - Dolfing, J.

AU - Janssen, D. B.

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AB - A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.

KW - 1,2-Dichloroethane

KW - Adaptation

KW - Chloroacetate

KW - Dehalogenase

KW - Evolution

KW - Trichloroethylene

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Degradation of halogenated aliphatic compounds: The role of adaptation

Abstract

Keywords

UN SDGs

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