Design and bio-applications of biological metal-organic frameworks

Baoting Sun, Muhammad Bilal, Shiru Jia*, Yunhong Jiang, Jiandong Cui

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

36 Citations (Scopus)


Biological metal-organic frameworks (bioMOFs) are a new subclass of the MOF family. In comparison with traditional MOFs, the bioMOFs are made of multifunctional biologically related ligands (bio-ligand) and metal ions. The bio-ligands confer biological compatibility for traditional MOFs, thus providing many opportunities for a wide array of biological applications. This review highlights the recent advances in the synthesis of bioMOFs comprising multifunctional bio-ligands and metal ions. These bio-ligands include nucleobases, amino acids, peptides, proteins, cyclodextrin, saccharides, and other biomolecules. Furthermore, the potential bio-applications of bioMOFs in several fields such as biomedicine, biosensing and bioimaging, antimicrobial applications, biomimetic catalysis, chiral separation, and environmental protection are also demonstrated.

Original languageEnglish
Pages (from-to)1949-1964
Number of pages16
JournalKorean Journal of Chemical Engineering
Issue number12
Early online date4 Dec 2019
Publication statusPublished - Dec 2019
Externally publishedYes


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