Design and optimisation of a microgripper : demonstration of biomedical applications using the manipulation of oocytes

B.P. Solano, Andrew Gallant, David Wood

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

14 Citations (Scopus)

Abstract

We present a bidirectional electrothermal microgripper for the advanced manipulation of single large cells. The device demonstrates excellent performance, and shows great potential as a supporting microtool for different biomedical procedures such as oocyte selection or electrofusion of cells. In particular, we focus on the operation of the device in real environments, i.e. integrated in a standard biological micromanipulation station and entirely submerged in a biological fluid, for the handling and transportation of ?live? specimens (in our case mice oocytes). A clamping mechanism is included in the design that limits the pressure exerted over the biological specimen to an approximate maximum of 40 ?N, whilst maintaining a robust grip, with a force up to 300 ?N, between the arms of the microgripper.
Original languageEnglish
Title of host publicationSymposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Rome, Italy, 1-3 April 2009.
EditorsT. Bourouina, B. Courtois, R. Ghodssi, A. Soma, H. Yang, J.M. Karam
Place of PublicationPiscataway, NJ
PublisherIEEE
Pages61-65
Number of pages5
ISBN (Print)978-1-4244-3874-7
Publication statusPublished - 1 May 2009

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