Detecting phase transitions in supercritical mixtures: an enabling tool for greener chemical reactions

Jie Ke, Yolanda Sanchez-Vicente, Geoffrey R. Akien, Alexander A. Novitskiy, Gurbuz Comak, Victor N. Bagratashvili, Michael W. George, Martyn Poliakoff

Research output: Contribution to journalReview articlepeer-review

15 Citations (Scopus)


Detecting phase transitions in high-pressure CO2 and supercritical fluids was first attempted in the nineteenth century. By contrast, Green Chemistry, the design and implementation of cleaner methods of manufacturing and processing chemicals, is barely 20 years old. Now, the use of CO2 as an environmentally more acceptable replacement for traditional solvents for greener chemical reactions is creating the need for new, more rapid methods for elucidating high-pressure phase behaviour. This paper describes the advantages and limitations of a number of approaches, developed in Nottingham, to meet this need, including acoustic measurements, shear-mode quartz sensors, the fibre-optic reflectometer, the use of holey fibres, attenuated total reflectance infrared spectroscopy and pressure drop measurements.
Original languageEnglish
Pages (from-to)2799-2818
Number of pages20
JournalProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Issue number2122
Early online date28 Jul 2010
Publication statusPublished - 8 Oct 2010
Externally publishedYes

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