Detection of exogenous VOCs as a novel in vitro diagnostic technique for the detection of pathogenic bacteria

Fraser Lough, John Perry, Stephen Stanforth, John Dean

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)
9 Downloads (Pure)

Abstract

The evolution of volatile organic compounds (VOCs) provides an opportunistic approach for the detection of pathogenic bacteria. This approach can be enhanced by the application of VOC-labelled enzyme substrates that target specific enzyme activities of the bacteria under investigation. Detection of the VOCs provides a novel, specific and sensitive approach for the detection of pathogenic bacteria. This review highlights the importance of this approach alongside a range of alternative detection techniques for the identification of pathogenic bacteria.
Original languageEnglish
Pages (from-to)71-81
JournalTrAC - Trends in Analytical Chemistry
Volume87
Early online date19 Dec 2016
DOIs
Publication statusPublished - Feb 2017

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