Three potential chromogenic enzymatic probes, each possessing a self-immolative spacer unit, were synthesised for the purpose of detecting L-alanylaminopeptidase activity in microorganisms. An Alizarin-based probe was the most effective, allowing several species to generate strongly coloured colonies in the presence of metal ions.
|Journal||Bioorganic & Medicinal Chemistry Letters|
|Early online date||28 Mar 2017|
|Publication status||Published - 15 May 2017|