Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry

Paul Bassarab; David Williams; John Dean; Edwin Ludkin; Justin Perry

doi:10.1016/j.chroma.2010.11.088

Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry

Paul Bassarab, David Williams, John Dean, Edwin Ludkin, Justin Perry

Applied Sciences Department

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

A method for the simultaneous determination of two biocidal quaternary ammonium compounds; didecyldimethylammonium chloride (didecyldimethyl quat) and dodecylbenzyldimethylammonium chloride (benzyl quat), in seawater by solid phase extraction (SPE) followed by liquid chromatography–mass spectrometry (LC–MS) was developed. The optimised procedure utilised off-line extraction of the analytes from seawater using polymeric (Strata-X) SPE cartridges. Recoveries ranged from 80 to 105%, with detection limits at the low parts-per-trillion (ng/l) level for both analytes. To demonstrate sensitivity, environmental concentrations were measured at three different locations along the North East coast of England with measured values in the range 120–270 ng/l.

Original language	English
Pages (from-to)	673-677
Journal	Journal of Chromatography A
Volume	1218
Issue number	5
DOIs	https://doi.org/10.1016/j.chroma.2010.11.088
Publication status	Published - Feb 2011

Keywords

Quaternary ammonium salts
Seawater-Analysis

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10.1016/j.chroma.2010.11.088

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title = "Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry",

abstract = "A method for the simultaneous determination of two biocidal quaternary ammonium compounds; didecyldimethylammonium chloride (didecyldimethyl quat) and dodecylbenzyldimethylammonium chloride (benzyl quat), in seawater by solid phase extraction (SPE) followed by liquid chromatography–mass spectrometry (LC–MS) was developed. The optimised procedure utilised off-line extraction of the analytes from seawater using polymeric (Strata-X) SPE cartridges. Recoveries ranged from 80 to 105%, with detection limits at the low parts-per-trillion (ng/l) level for both analytes. To demonstrate sensitivity, environmental concentrations were measured at three different locations along the North East coast of England with measured values in the range 120–270 ng/l.",

keywords = "Quaternary ammonium salts, Seawater-Analysis",

author = "Paul Bassarab and David Williams and John Dean and Edwin Ludkin and Justin Perry",

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TY - JOUR

T1 - Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry

AU - Bassarab, Paul

AU - Williams, David

AU - Dean, John

AU - Ludkin, Edwin

AU - Perry, Justin

PY - 2011/2

Y1 - 2011/2

N2 - A method for the simultaneous determination of two biocidal quaternary ammonium compounds; didecyldimethylammonium chloride (didecyldimethyl quat) and dodecylbenzyldimethylammonium chloride (benzyl quat), in seawater by solid phase extraction (SPE) followed by liquid chromatography–mass spectrometry (LC–MS) was developed. The optimised procedure utilised off-line extraction of the analytes from seawater using polymeric (Strata-X) SPE cartridges. Recoveries ranged from 80 to 105%, with detection limits at the low parts-per-trillion (ng/l) level for both analytes. To demonstrate sensitivity, environmental concentrations were measured at three different locations along the North East coast of England with measured values in the range 120–270 ng/l.

AB - A method for the simultaneous determination of two biocidal quaternary ammonium compounds; didecyldimethylammonium chloride (didecyldimethyl quat) and dodecylbenzyldimethylammonium chloride (benzyl quat), in seawater by solid phase extraction (SPE) followed by liquid chromatography–mass spectrometry (LC–MS) was developed. The optimised procedure utilised off-line extraction of the analytes from seawater using polymeric (Strata-X) SPE cartridges. Recoveries ranged from 80 to 105%, with detection limits at the low parts-per-trillion (ng/l) level for both analytes. To demonstrate sensitivity, environmental concentrations were measured at three different locations along the North East coast of England with measured values in the range 120–270 ng/l.

KW - Quaternary ammonium salts

KW - Seawater-Analysis

U2 - 10.1016/j.chroma.2010.11.088

DO - 10.1016/j.chroma.2010.11.088

M3 - Article

SN - 0021-9673

VL - 1218

SP - 673

EP - 677

JO - Journal of Chromatography A

JF - Journal of Chromatography A

IS - 5

ER -

Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry

Abstract

Keywords

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