Determination of quaternary ammonium compounds in seawater samples by solid-phase extraction and liquid chromatography–mass spectrometry

Paul Bassarab, David Williams, John Dean, Edwin Ludkin, Justin Perry

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

A method for the simultaneous determination of two biocidal quaternary ammonium compounds; didecyldimethylammonium chloride (didecyldimethyl quat) and dodecylbenzyldimethylammonium chloride (benzyl quat), in seawater by solid phase extraction (SPE) followed by liquid chromatography–mass spectrometry (LC–MS) was developed. The optimised procedure utilised off-line extraction of the analytes from seawater using polymeric (Strata-X) SPE cartridges. Recoveries ranged from 80 to 105%, with detection limits at the low parts-per-trillion (ng/l) level for both analytes. To demonstrate sensitivity, environmental concentrations were measured at three different locations along the North East coast of England with measured values in the range 120–270 ng/l.
Original languageEnglish
Pages (from-to)673-677
JournalJournal of Chromatography A
Volume1218
Issue number5
DOIs
Publication statusPublished - Feb 2011

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