Development of the neonatal microbiota

Gregory Young; Stefan Zalewski; Stephen Cummings; Clare Lanyon

doi:10.3920/978-90-8686-839-1_2

Development of the neonatal microbiota

Gregory Young, Stefan Zalewski, Stephen Cummings, Clare Lanyon

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The period immediately following birth is vital to the development of a healthy neonatal intestinal microbiome. As any environment the primary colonisers of the neonatal gastrointestinal tract pave the way for further colonisation. For this reason the first 18 months of life are considered crucial to the development of a healthy neonatal microbiota. When regular preliminary colonisation fails to proceed, the fine balance between the numerous members of the microbiota can be disturbed, which can manifest in a number of disease states, including necrotising enterocolitis and neonatal sepsis. This chapter aims to identify the differences between and possible causes of bacterial symbiosis and dysbiosis within the neonatal gastrointestinal tract. The pathology of associated disease states will also be explained.

Original language	English
Title of host publication	Microbiota in health and disease
Subtitle of host publication	from pregnancy to childhood
Editors	Pamela D. Browne, Eric Claassen, Michael D. Cabana
Place of Publication	Wageningen
Publisher	Wageningen Academic Publishers
Chapter	2
Pages	39-56
Number of pages	344
ISBN (Print)	9789086862948
DOIs	https://doi.org/10.3920/978-90-8686-839-1_2
Publication status	Published - 20 Jul 2017

Keywords

diseases of infancy
treatment
prevention
symbiosis
dysbiosis
immune response

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10.3920/978-90-8686-839-1_2

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AU - Lanyon, Clare

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Development of the neonatal microbiota

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Keywords

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