TY - JOUR
T1 - Diagnosis and Monitoring of Alzheimer's Patients Using Classical and Deep Learning Techniques
AU - Raza, Mohsin
AU - Awais, Muhammad
AU - Ellahi, Waqas
AU - Aslam, Nauman
AU - Nguyen, Huan X.
AU - Le Minh, Hoa
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Machine based analysis and prediction systems are widely used for diagnosis of Alzheimer's Disease (AD). However, lower accuracy of existing techniques and lack of post diagnosis monitoring systems limit the scope of such studies. In this paper, a novel machine learning based diagnosis and monitoring of AD-like diseases is proposed. The AD-like diseases diagnosis process is accomplished by analysing the magnetic resonance imaging (MRI) scans using deep learning and is followed by an activity monitoring framework to monitor the subjects’ activities of daily living using body worn inertial sensors. The activity monitoring provides an assistive framework in daily life activities and evaluates vulnerability of the patients based on the activity level. The AD diagnosis results show up to 82% improvement in comparison to well-known existing techniques. Moreover, above 95% accuracy is achieved to classify the activities of daily living which is quite encouraging in terms of monitoring the activity profile of the subject.
AB - Machine based analysis and prediction systems are widely used for diagnosis of Alzheimer's Disease (AD). However, lower accuracy of existing techniques and lack of post diagnosis monitoring systems limit the scope of such studies. In this paper, a novel machine learning based diagnosis and monitoring of AD-like diseases is proposed. The AD-like diseases diagnosis process is accomplished by analysing the magnetic resonance imaging (MRI) scans using deep learning and is followed by an activity monitoring framework to monitor the subjects’ activities of daily living using body worn inertial sensors. The activity monitoring provides an assistive framework in daily life activities and evaluates vulnerability of the patients based on the activity level. The AD diagnosis results show up to 82% improvement in comparison to well-known existing techniques. Moreover, above 95% accuracy is achieved to classify the activities of daily living which is quite encouraging in terms of monitoring the activity profile of the subject.
KW - Activities of Daily Life (ADLs)
KW - Alzheimer Disease (AD)
KW - Deep Neural Networks
KW - Machine learning
KW - Magnetic Resonance Imaging (MRI)
KW - Support Vector Machine (SVM)
UR - http://www.scopus.com/inward/record.url?scp=85068119313&partnerID=8YFLogxK
U2 - 10.1016/j.eswa.2019.06.038
DO - 10.1016/j.eswa.2019.06.038
M3 - Article
VL - 136
SP - 353
EP - 364
JO - Expert Systems with Applications
JF - Expert Systems with Applications
SN - 0957-4174
ER -