Domain-ligand mapping for enzymes

Matthew Bashton, Janet M Thornton

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)


In this paper we provide an overview of our current knowledge of the mapping between small molecule ligands and protein domains. We give an overview of the present data resources available on the Web, which provide information about protein-ligand interactions, as well as discussing our own PROCOGNATE database. We present an update of ligand binding in large protein superfamilies and identify those ligands most frequently utilized by nature. Finally we discuss potential uses for this type of data.

Original languageEnglish
Pages (from-to)194-208
Number of pages15
JournalJournal of Molecular Recognition
Issue number2
Early online date6 Oct 2009
Publication statusPublished - 1 Mar 2010
Externally publishedYes


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