In this paper we provide an overview of our current knowledge of the mapping between small molecule ligands and protein domains. We give an overview of the present data resources available on the Web, which provide information about protein-ligand interactions, as well as discussing our own PROCOGNATE database. We present an update of ligand binding in large protein superfamilies and identify those ligands most frequently utilized by nature. Finally we discuss potential uses for this type of data.
|Number of pages||15|
|Journal||Journal of Molecular Recognition|
|Early online date||6 Oct 2009|
|Publication status||Published - 1 Mar 2010|