@article{5d1f6003432542e08e2982e60dec34dd,
title = "Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones",
abstract = "A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively. Domino reactions were performed under microwave irradiation leading to desired compounds in a few minutes and high yields",
keywords = "domino reaction, 2-aminothiazole, thiazolopyrimidinone, microwave synthesis, antiviral agents",
author = "Maurizio Botta and Daniele Castagnolo and Mafalda Pagano and Martina Bernardini",
year = "2009",
doi = "10.1055/s-0029-1217700",
language = "English",
volume = "2009",
pages = "2093--2096",
journal = "Synlett",
issn = "0936-5214",
publisher = "Georg Thieme Verlag",
number = "13",
}