Dynamic model of gene regulation for the lac operon

Maia Angelova, Asma Ahmed Ben-Halim

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria. In this work we consider a deterministic model of the lac operon with a noise term, representing the stochastic nature of the regulation. The model is written in terms of a system of simultaneous first order differential equations with delays. We investigate an analytical and numerical solution and analyse the range of values for the parameters corresponding to a stable solution.
Original languageEnglish
JournalJournal of Physics: Conference Series
Volume286
Issue number1
DOIs
Publication statusPublished - 2011

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