A novel microwave imaging approach for early stage breast cancer detection is described. The proposed technique involves the use of an Indirect Microwave Holographic technique employing a patented synthetic reference wave. This approach offers benefits in terms of simplicity, expense, comfort and safety when compared to current mammography techniques. Experimental results using a simulated breast phantom are included to demonstrate the validity of this technique to obtain 2D images. The technique is then extended to demonstrate the possibility of obtaining 3D images by using indirect stereoscopic holographic imaging.