TY - JOUR
T1 - Ecological impact of antibiotics on bioremediation performance of constructed wetlands
T2 - Microbial and plant dynamics, and potential antibiotic resistance genes hotspots
AU - Ohore, Okugbe Ebiotubo
AU - Qin, Zhirui
AU - Sanganyado, Edmond
AU - Wang, Yuwen
AU - Jiao, Xiaoyang
AU - Liu, Wenhua
AU - Wang, Zhen
N1 - Funding Information: This work research was supported by the National Natural Science Foundation of China, China (21906067), Shantou University Scientific Research Foundation for Talents, China (NTF19044), 2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant, China (2020LKSFG03E), and Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), China (GML2019ZD0606).
PY - 2022/2/15
Y1 - 2022/2/15
N2 - Constructed wetlands (CWs) are nature-based solutions for treating domestic and livestock wastewater which may contain residual antibiotics concentration. Antibiotics may exert selection pressure on wetland's microbes, thereby increasing the global antibiotics resistance problems. This review critically examined the chemodynamics of antibiotics and antibiotics resistance genes (ARGs) in CWs. Antibiotics affected the biogeochemical cycling function of microbial communities in CWs and directly disrupted the removal efficiency of total nitrogen, total phosphorus, and chemical oxygen demand by 22%, 9.3%, and 24%, respectively. Since changes in microbial function and structure are linked to the emergence and propagation of antibiotic resistance, antibiotics could adversely affect microbial diversity in CWs. The cyanobacteria community seemed to be particularly vulnerable, while Proteobacteria could resist and persist in antibiotics contaminated wetlands. Antibiotics triggered excitation responses in plants and increased the root activities and exudates. Microbes, plants, and substrates play crucial roles in antibiotic removal. High removal efficiency was exhibited for triclosan (100%) > enrofloxacin (99.8%) > metronidazole (99%) > tetracycline (98.8%) > chlortetracycline (98.4%) > levofloxacin (96.69%) > sulfamethoxazole (91.9%) by the CWs. This review showed that CWs exhibited high antibiotics removal capacity, but the absolute abundance of ARGs increased, suggesting CWs are potential hotspots for ARGs. Future research should focus on specific bacterial response and impact on microbial interactions.
AB - Constructed wetlands (CWs) are nature-based solutions for treating domestic and livestock wastewater which may contain residual antibiotics concentration. Antibiotics may exert selection pressure on wetland's microbes, thereby increasing the global antibiotics resistance problems. This review critically examined the chemodynamics of antibiotics and antibiotics resistance genes (ARGs) in CWs. Antibiotics affected the biogeochemical cycling function of microbial communities in CWs and directly disrupted the removal efficiency of total nitrogen, total phosphorus, and chemical oxygen demand by 22%, 9.3%, and 24%, respectively. Since changes in microbial function and structure are linked to the emergence and propagation of antibiotic resistance, antibiotics could adversely affect microbial diversity in CWs. The cyanobacteria community seemed to be particularly vulnerable, while Proteobacteria could resist and persist in antibiotics contaminated wetlands. Antibiotics triggered excitation responses in plants and increased the root activities and exudates. Microbes, plants, and substrates play crucial roles in antibiotic removal. High removal efficiency was exhibited for triclosan (100%) > enrofloxacin (99.8%) > metronidazole (99%) > tetracycline (98.8%) > chlortetracycline (98.4%) > levofloxacin (96.69%) > sulfamethoxazole (91.9%) by the CWs. This review showed that CWs exhibited high antibiotics removal capacity, but the absolute abundance of ARGs increased, suggesting CWs are potential hotspots for ARGs. Future research should focus on specific bacterial response and impact on microbial interactions.
KW - Antibiotic resistance genes
KW - Antibiotics removal
KW - Bibliometric analysis
KW - Constructed wetlands
KW - Nutrient cycling
KW - Wastewater treatment plants
UR - http://www.scopus.com/inward/record.url?scp=85117179269&partnerID=8YFLogxK
U2 - 10.1016/j.jhazmat.2021.127495
DO - 10.1016/j.jhazmat.2021.127495
M3 - Review article
C2 - 34673400
AN - SCOPUS:85117179269
SN - 0304-3894
VL - 424
JO - Journal of Hazardous Materials
JF - Journal of Hazardous Materials
IS - Part B
M1 - 127495
ER -