TY - JOUR
T1 - Effect of physical activity on the relationship between adiposity and cardiac autonomic modulation in female breast cancer survivors
T2 - a longitudinal study
AU - Palma, Mariana R.
AU - Tebar, William R.
AU - Beretta, Victor Spiandor
AU - Vanderlei, Luiz Carlos Marques
AU - Fregonesi, Cristina E.P.T.
AU - Ribeiro, Fernanda E.
AU - Caldeira, Daniela T.
AU - Ramos, Ercy M.C.
AU - Cucato, Gabriel G.
AU - Ferrari, Gerson
AU - Ritti-Dias, Raphael Mendes
AU - Christofaro, Diego Giulliano Destro
N1 - Funding information: The authors would like to thank the Coordination for the Improvement of Higher Education Personnel (Capes) [Finance code 001] for financial scholarship to MRP. DGDC and RMRD holds a Productivity Fellowship from the National Council for Scientific and Technological Development (Grant number: 305886/2022-3 and 308954/2021-1).
PY - 2024/2/7
Y1 - 2024/2/7
N2 - This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body adiposity through electrical bioimpedance considering body fat percentage (BFP), CAM through heart rate variability (considering RMSSD, SDNN, PNN50, LF (m2), HF (m2), SD1 indexes and SD1/SD2 ratio) and PA through a questionnaire in 64 participants (58.0 ± 9.6 years), recruited through the local association of support for breast cancer and by direct indications from city mastologists. After insertion of PA into the multivariate statistical model, significant attenuation was observed in the relationship between body adiposity and CAM for the indices: SDNN (β = −0.94; 95 percent CI: −1.93; 0.04; p =.060) and SD1/SD2 (β = −0.01;95 percent CI = −0.02; 0.001; p =.065). In conclusion, it was observed that PA was able to mitigate the relationships between BFP and CAM (considering SDNN index and SD1/SD2 ratio) in breast cancer survivors.
AB - This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body adiposity through electrical bioimpedance considering body fat percentage (BFP), CAM through heart rate variability (considering RMSSD, SDNN, PNN50, LF (m2), HF (m2), SD1 indexes and SD1/SD2 ratio) and PA through a questionnaire in 64 participants (58.0 ± 9.6 years), recruited through the local association of support for breast cancer and by direct indications from city mastologists. After insertion of PA into the multivariate statistical model, significant attenuation was observed in the relationship between body adiposity and CAM for the indices: SDNN (β = −0.94; 95 percent CI: −1.93; 0.04; p =.060) and SD1/SD2 (β = −0.01;95 percent CI = −0.02; 0.001; p =.065). In conclusion, it was observed that PA was able to mitigate the relationships between BFP and CAM (considering SDNN index and SD1/SD2 ratio) in breast cancer survivors.
KW - Autonomic nervous system
KW - body fat
KW - breast neoplasms
KW - exercise
KW - heart rate
UR - http://www.scopus.com/inward/record.url?scp=85182458047&partnerID=8YFLogxK
U2 - 10.1080/03630242.2024.2305342
DO - 10.1080/03630242.2024.2305342
M3 - Article
C2 - 38229419
AN - SCOPUS:85182458047
SN - 0363-0242
VL - 64
SP - 165
EP - 174
JO - Women and Health
JF - Women and Health
IS - 2
ER -
