TY - JOUR
T1 - Effects of isometric handgrip training on blood pressure among hypertensive patients seen within public primary healthcare
T2 - a randomized controlled trial
AU - Palmeira, Aline Cabral
AU - Farah, Breno Quintella
AU - Silva, Gustavo Oliveira da
AU - Moreira, Sérgio Rodrigues
AU - Barros, Mauro Virgílio Gomes de
AU - Correia, Marilia de Almeida
AU - Cucato, Gabriel Grizzo
AU - Ritti-Dias, Raphael Mendes
N1 - Funding information: RMRD and MVGB held research productivity fellowships granted by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), grant number 310508/2017-7, and Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco (FACEPE), grant number 1177-4.09/14. This study was also supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), grant number 01.
PY - 2021/12
Y1 - 2021/12
N2 - BACKGROUND:Meta-analyses have demonstrated that isometric handgrip training (IHT) decreases blood pressure in hypertensive individuals. Nonetheless, most studies were conducted in laboratory settings and its effects in real-world settings remain unclear.OBJECTIVE:To analyze the effects of IHT on office and ambulatory blood pressure in hypertensive patients attended within primary healthcare.DESIGN AND SETTING:Randomized controlled trial conducted in primary healthcare units within the Family Health Program, Petrolina, Pernambuco, Brazil.METHODS:63 hypertensive patients (30-79 years old; 70% female) were randomly allocated into IHT or control groups. IHT was performed three times per week (4 x 2 minutes at 30% of maximal voluntary contraction, one-minute rest between bouts, alternating the hands). Before and after the 12-week training period, office and ambulatory blood pressure and heart rate variability were obtained. The significance level was set at P < 0.05 (two-tailed testing) for all analyses.RESULTS:IHT significantly decreased office systolic blood pressure (IHT: 129 ± 4 versus 121 ± 3 mmHg, P < 0.05; control: 126 ± 4 versus 126 ± 3 mmHg, P > 0.05), whereas there was no effect on diastolic blood pressure (IHT: 83 ± 3 versus 79 ± 2 mmHg, P > 0.05; control: 81 ± 3 versus 77 ± 3 mmHg, P > 0.05). Heart rate variability and ambulatory blood pressure were not altered by the interventions (P > 0.05 for all).CONCLUSION:IHT reduced office systolic blood pressure in hypertensive patients attended within primary care. However, there were effects regarding diastolic blood pressure, ambulatory blood pressure or heart rate variability.CLINICALTRIALS.GOV IDENTIFIER:NCT03216317.
AB - BACKGROUND:Meta-analyses have demonstrated that isometric handgrip training (IHT) decreases blood pressure in hypertensive individuals. Nonetheless, most studies were conducted in laboratory settings and its effects in real-world settings remain unclear.OBJECTIVE:To analyze the effects of IHT on office and ambulatory blood pressure in hypertensive patients attended within primary healthcare.DESIGN AND SETTING:Randomized controlled trial conducted in primary healthcare units within the Family Health Program, Petrolina, Pernambuco, Brazil.METHODS:63 hypertensive patients (30-79 years old; 70% female) were randomly allocated into IHT or control groups. IHT was performed three times per week (4 x 2 minutes at 30% of maximal voluntary contraction, one-minute rest between bouts, alternating the hands). Before and after the 12-week training period, office and ambulatory blood pressure and heart rate variability were obtained. The significance level was set at P < 0.05 (two-tailed testing) for all analyses.RESULTS:IHT significantly decreased office systolic blood pressure (IHT: 129 ± 4 versus 121 ± 3 mmHg, P < 0.05; control: 126 ± 4 versus 126 ± 3 mmHg, P > 0.05), whereas there was no effect on diastolic blood pressure (IHT: 83 ± 3 versus 79 ± 2 mmHg, P > 0.05; control: 81 ± 3 versus 77 ± 3 mmHg, P > 0.05). Heart rate variability and ambulatory blood pressure were not altered by the interventions (P > 0.05 for all).CONCLUSION:IHT reduced office systolic blood pressure in hypertensive patients attended within primary care. However, there were effects regarding diastolic blood pressure, ambulatory blood pressure or heart rate variability.CLINICALTRIALS.GOV IDENTIFIER:NCT03216317.
KW - Cardiac autonomic modulation
KW - Strength training
KW - Primary care
KW - Isometric
UR - http://www.scopus.com/inward/record.url?scp=85121430529&partnerID=8YFLogxK
U2 - 10.1590/1516-3180.2020.0796.r1.22042021
DO - 10.1590/1516-3180.2020.0796.r1.22042021
M3 - Article
SN - 1516-3180
VL - 139
SP - 648
EP - 656
JO - Sao Paulo Medical Journal
JF - Sao Paulo Medical Journal
IS - 6
ER -