TY - JOUR
T1 - Efficacy of intracameral and subconjunctival cefuroxime in preventing endophthalmitis after cataract surgery
AU - Yu-Wai-Man, Patrick
AU - Morgan, Stephen
AU - Hildreth, Anthony
AU - Steel, David
AU - Allen, David
PY - 2008
Y1 - 2008
N2 - Purpose
To compare the efficacy of intracameral cefuroxime versus subconjunctival cefuroxime in reducing the rate of endophthalmitis after cataract surgery.
Setting
Single-specialty eye hospital, Sunderland, United Kingdom.
Methods
A retrospective analysis of all presumed infectious endophthalmitis cases from January 1, 2000, to December 31, 2006 was performed. The rate of presumed infectious endophthalmitis in patients receiving subconjunctival cefuroxime was compared with those receiving intracameral cefuroxime at the end of surgery.
Results
This study included 36743 phacoemulsification cataract procedures. The mean rate of presumed infectious endophthalmitis was 0.95 per 1000 cases. The incidence of endophthalmitis was higher in the subconjunctival cefuroxime group than in the intracameral cefuroxime group; the difference was statistically significant with an odds ratio of 3.01 (95% confidence interval, 1.37-6.63). Conclusion Intracameral cefuroxime was a safe alternative to subconjunctival cefuroxime and led to a lower rate of endophthalmitis
AB - Purpose
To compare the efficacy of intracameral cefuroxime versus subconjunctival cefuroxime in reducing the rate of endophthalmitis after cataract surgery.
Setting
Single-specialty eye hospital, Sunderland, United Kingdom.
Methods
A retrospective analysis of all presumed infectious endophthalmitis cases from January 1, 2000, to December 31, 2006 was performed. The rate of presumed infectious endophthalmitis in patients receiving subconjunctival cefuroxime was compared with those receiving intracameral cefuroxime at the end of surgery.
Results
This study included 36743 phacoemulsification cataract procedures. The mean rate of presumed infectious endophthalmitis was 0.95 per 1000 cases. The incidence of endophthalmitis was higher in the subconjunctival cefuroxime group than in the intracameral cefuroxime group; the difference was statistically significant with an odds ratio of 3.01 (95% confidence interval, 1.37-6.63). Conclusion Intracameral cefuroxime was a safe alternative to subconjunctival cefuroxime and led to a lower rate of endophthalmitis
U2 - 10.1016/j.jcrs.2007.10.041
DO - 10.1016/j.jcrs.2007.10.041
M3 - Article
SN - 0886-3350
VL - 34
SP - 447
EP - 451
JO - Journal of Cataract and Refractive Surgery
JF - Journal of Cataract and Refractive Surgery
IS - 3
ER -