Abstract
A novel method is proposed for quantifying the Raman intensity as a function of gold mass in a single cell based on the Raman mapping and inductively coupled plasma-mass spectrometry techniques. And a high-efficiency plasmonic photothermal therapy has also been achieved by adjusting the laser wavelength, laser power and exposure time, resulting in most of the HL-7702 cells survive, whereas most of the HepG2 cells get damaged.
Original language | English |
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Pages (from-to) | 2245-2259 |
Journal | Nanomedicine |
Volume | 13 |
Issue number | 18 |
Early online date | 3 Oct 2018 |
DOIs | |
Publication status | E-pub ahead of print - 3 Oct 2018 |
Keywords
- cellular uptake
- human hepatic immortalized cell lines (HL-7702)
- cytotoxicity
- gold nanoparticles
- human hepatocellular carcinoma cell lines (HepG2)
- ICP-MS
- plasmonic photothermal therapy
- Raman mapping
- Surface enhanced Raman scattering (SERS)