Evaluating Patterns and Factors Related to Sleep Disturbances in Prostate Cancer Patients

Shalini Mondal; Steve Edwards; Erik Wibowo; Hashim Ahmed; Richard J. Wassersug; Jason Ellis; Maximus Isaac; Dagmara Dimitriou; Stephen Mangar

doi:10.3390/healthcare10050832

Evaluating Patterns and Factors Related to Sleep Disturbances in Prostate Cancer Patients

Shalini Mondal, Steve Edwards, Erik Wibowo, Hashim Ahmed, Richard J. Wassersug, Jason Ellis, Maximus Isaac, Dagmara Dimitriou^*, Stephen Mangar^*

^*Corresponding author for this work

Psychology Department

Research output: Contribution to journal › Article › peer-review

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Abstract

Prostate cancer patients may experience disturbed sleep as a result of their diagnosis or treatment. This study sought to evaluate disturbed sleep and excessive daytime sleepiness in newly diagnosed patients and those receiving androgen deprivation therapy (ADT). This study was conducted with 74 patients. Subjective data using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) and actigraphy data on ADT/ADT-naïve patients were collected. The prevalence of poor sleep quality, determined from PSQI and ESS scores, was 50% and 16.7% respectively. Those on ADT (n = 20) had poorer sleep quality as determined by significantly higher PSQI scores (70 vs. 40% scoring > 5) and were more likely to have poor sleep quality, sleep latency, and sleep efficiency than ADT-naïve patients (n = 40). Actigraphy data showed that ADT patients slept significantly longer (7.7 vs. 6.8 h), experienced a higher Fragmentation Index (48.3 vs. 37.4%), and had longer daytime nap duration (64.1 vs. 45.2 min) than ADT-naïve patients. The use of objective measures such as actigraphy in the clinical arena is recommended and may be used as a valuable tool for research into sleep assessment in prostate cancer patients.

Original language	English
Article number	832
Number of pages	12
Journal	Healthcare (Switzerland)
Volume	10
Issue number	5
DOIs	https://doi.org/10.3390/healthcare10050832
Publication status	Published - 30 Apr 2022

Keywords

sleep
insomnia
prostate cancer
actigraphy
sleep fragmentation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Evaluating Patterns and Factors Related to Sleep Disturbances in Prostate Cancer Patients",

abstract = "Prostate cancer patients may experience disturbed sleep as a result of their diagnosis or treatment. This study sought to evaluate disturbed sleep and excessive daytime sleepiness in newly diagnosed patients and those receiving androgen deprivation therapy (ADT). This study was conducted with 74 patients. Subjective data using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) and actigraphy data on ADT/ADT-na{\"i}ve patients were collected. The prevalence of poor sleep quality, determined from PSQI and ESS scores, was 50% and 16.7% respectively. Those on ADT (n = 20) had poorer sleep quality as determined by significantly higher PSQI scores (70 vs. 40% scoring > 5) and were more likely to have poor sleep quality, sleep latency, and sleep efficiency than ADT-na{\"i}ve patients (n = 40). Actigraphy data showed that ADT patients slept significantly longer (7.7 vs. 6.8 h), experienced a higher Fragmentation Index (48.3 vs. 37.4%), and had longer daytime nap duration (64.1 vs. 45.2 min) than ADT-na{\"i}ve patients. The use of objective measures such as actigraphy in the clinical arena is recommended and may be used as a valuable tool for research into sleep assessment in prostate cancer patients.",

keywords = "sleep, insomnia, prostate cancer, actigraphy, sleep fragmentation",

author = "Shalini Mondal and Steve Edwards and Erik Wibowo and Hashim Ahmed and Wassersug, {Richard J.} and Jason Ellis and Maximus Isaac and Dagmara Dimitriou and Stephen Mangar",

note = "Funding information: This work is supported by funding from Mangar{\textquoteright}s Cancer Research Fund, Imperial College, London.",

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AU - Mondal, Shalini

AU - Edwards, Steve

AU - Wibowo, Erik

AU - Ahmed, Hashim

AU - Wassersug, Richard J.

AU - Ellis, Jason

AU - Isaac, Maximus

AU - Dimitriou, Dagmara

AU - Mangar, Stephen

N1 - Funding information: This work is supported by funding from Mangar’s Cancer Research Fund, Imperial College, London.

PY - 2022/4/30

Y1 - 2022/4/30

N2 - Prostate cancer patients may experience disturbed sleep as a result of their diagnosis or treatment. This study sought to evaluate disturbed sleep and excessive daytime sleepiness in newly diagnosed patients and those receiving androgen deprivation therapy (ADT). This study was conducted with 74 patients. Subjective data using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) and actigraphy data on ADT/ADT-naïve patients were collected. The prevalence of poor sleep quality, determined from PSQI and ESS scores, was 50% and 16.7% respectively. Those on ADT (n = 20) had poorer sleep quality as determined by significantly higher PSQI scores (70 vs. 40% scoring > 5) and were more likely to have poor sleep quality, sleep latency, and sleep efficiency than ADT-naïve patients (n = 40). Actigraphy data showed that ADT patients slept significantly longer (7.7 vs. 6.8 h), experienced a higher Fragmentation Index (48.3 vs. 37.4%), and had longer daytime nap duration (64.1 vs. 45.2 min) than ADT-naïve patients. The use of objective measures such as actigraphy in the clinical arena is recommended and may be used as a valuable tool for research into sleep assessment in prostate cancer patients.

AB - Prostate cancer patients may experience disturbed sleep as a result of their diagnosis or treatment. This study sought to evaluate disturbed sleep and excessive daytime sleepiness in newly diagnosed patients and those receiving androgen deprivation therapy (ADT). This study was conducted with 74 patients. Subjective data using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) and actigraphy data on ADT/ADT-naïve patients were collected. The prevalence of poor sleep quality, determined from PSQI and ESS scores, was 50% and 16.7% respectively. Those on ADT (n = 20) had poorer sleep quality as determined by significantly higher PSQI scores (70 vs. 40% scoring > 5) and were more likely to have poor sleep quality, sleep latency, and sleep efficiency than ADT-naïve patients (n = 40). Actigraphy data showed that ADT patients slept significantly longer (7.7 vs. 6.8 h), experienced a higher Fragmentation Index (48.3 vs. 37.4%), and had longer daytime nap duration (64.1 vs. 45.2 min) than ADT-naïve patients. The use of objective measures such as actigraphy in the clinical arena is recommended and may be used as a valuable tool for research into sleep assessment in prostate cancer patients.

KW - sleep

KW - insomnia

KW - prostate cancer

KW - actigraphy

KW - sleep fragmentation

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Evaluating Patterns and Factors Related to Sleep Disturbances in Prostate Cancer Patients

Abstract

Keywords

UN SDGs

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