TY - JOUR
T1 - Expanding the Use of Six-Minute Walking Test in Patients with Intermittent Claudication
AU - Ritti-Dias, Raphael Mendes
AU - Sant'anna, Fernando da Silva
AU - Braghieri, Heloisa Amaral
AU - Wolosker, Nelson
AU - Puech-Leao, Pedro
AU - Lanza, Fernanda Cordoba
AU - Cucato, Gabriel Grizzo
AU - Dal Corso, Simone
AU - Correia, Marilia Almeida
N1 - Funding Information:
Funding: This study was supported by grants of Brazilian National Council for Scientific and Technological Development (CNPq #409707/2016-3). In addition, RR, NW, and SD hold a research productivity fellowship granted by CNPq. This study is also supported by Coordination for the Improvement of Higher Education Personnel, Brazil.
Publisher Copyright:
© 2020 Elsevier Inc.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - Background: Six-min walking test (6MWT) has been widely in patients with symptomatic peripheral artery disease (PAD) to quantify the walking impairment and the efficacy of different therapeutic interventions. Despite the aforementioned usefulness of 6MWT for PAD, the information provided by this test goes beyond the meters walked. The aim of this study was to describe the relative values of 6MWT and body weight–walking distance product (DW) in patients with symptomatic PAD. Methods: Two hundred twenty-seven patients with symptomatic PAD participated in the study. The 6MWT was performed and absolute and claudication distances were obtained. The results of 6MWT were then relativized and expressed as a percentage of a healthy subject. DW was obtained by the product of 6MWT distance by weight. In both sexes, the relative 6MWT ranged from 57% to 64%. Results: Absolute 6MWT total distance (P < 0.001) was lower in women than in men, whereas the relative 6MWT total distance was similar between sexes (P = 0.398). The absolute and relative 6MWT total distance were similar among age categories (P > 0.072). The DW was higher in men than in women (P < 0.05). In addition, in women, DW was higher in younger group than in other age groups (P < 0.05). Conclusions: Patients with symptomatic PAD achieve less than 70% of the distance achieved by an age-matched healthy subject. In patients with symptomatic PAD, the relative values of 6MWT total distance are similar between sexes and among different age groups, whereas DW are influenced by age and sex.
AB - Background: Six-min walking test (6MWT) has been widely in patients with symptomatic peripheral artery disease (PAD) to quantify the walking impairment and the efficacy of different therapeutic interventions. Despite the aforementioned usefulness of 6MWT for PAD, the information provided by this test goes beyond the meters walked. The aim of this study was to describe the relative values of 6MWT and body weight–walking distance product (DW) in patients with symptomatic PAD. Methods: Two hundred twenty-seven patients with symptomatic PAD participated in the study. The 6MWT was performed and absolute and claudication distances were obtained. The results of 6MWT were then relativized and expressed as a percentage of a healthy subject. DW was obtained by the product of 6MWT distance by weight. In both sexes, the relative 6MWT ranged from 57% to 64%. Results: Absolute 6MWT total distance (P < 0.001) was lower in women than in men, whereas the relative 6MWT total distance was similar between sexes (P = 0.398). The absolute and relative 6MWT total distance were similar among age categories (P > 0.072). The DW was higher in men than in women (P < 0.05). In addition, in women, DW was higher in younger group than in other age groups (P < 0.05). Conclusions: Patients with symptomatic PAD achieve less than 70% of the distance achieved by an age-matched healthy subject. In patients with symptomatic PAD, the relative values of 6MWT total distance are similar between sexes and among different age groups, whereas DW are influenced by age and sex.
UR - http://www.scopus.com/inward/record.url?scp=85090751074&partnerID=8YFLogxK
U2 - 10.1016/j.avsg.2020.07.047
DO - 10.1016/j.avsg.2020.07.047
M3 - Article
C2 - 32800882
AN - SCOPUS:85090751074
SN - 0890-5096
VL - 70
SP - 258
EP - 262
JO - Annals of Vascular Surgery
JF - Annals of Vascular Surgery
ER -