Extraction of tanshinone IIA from Salvia miltiorrhiza bunge using supercritical fluid extraction and a new extraction technique, phytosol solvent extraction

John Dean, B. Liu, R. Price

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Supercritical carbon dioxide with and without a methanol modifier has been compared with a new portable cold extraction technique, phytosol solvent extraction (PSE), for the extraction of Tanshinone IIA from Salvia miltiorrhiza bunge. High-performance liquid chromatography was used to analyse the extracts. The results show that the yield extracted by 10% methanol-modified supercritical carbon dioxide was the highest (0.038%, w/w) and the yields extracted by supercritical carbon dioxide at 60°C and 250 kg/cm2 and phytosol solvents (A,B and D) were similar (0.029-0.032%, w/w).
Original languageEnglish
Pages (from-to)343-348
JournalJournal of Chromatography A
Volume799
Issue number1-2
DOIs
Publication statusPublished - 13 Mar 1998

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