TY - JOUR
T1 - Extraction of tanshinone IIA from Salvia miltiorrhiza bunge using supercritical fluid extraction and a new extraction technique, phytosol solvent extraction
AU - Dean, John
AU - Liu, B.
AU - Price, R.
PY - 1998/3/13
Y1 - 1998/3/13
N2 - Supercritical carbon dioxide with and without a methanol modifier has been compared with a new portable cold extraction technique, phytosol solvent extraction (PSE), for the extraction of Tanshinone IIA from Salvia miltiorrhiza bunge. High-performance liquid chromatography was used to analyse the extracts. The results show that the yield extracted by 10% methanol-modified supercritical carbon dioxide was the highest (0.038%, w/w) and the yields extracted by supercritical carbon dioxide at 60°C and 250 kg/cm2 and phytosol solvents (A,B and D) were similar (0.029-0.032%, w/w).
AB - Supercritical carbon dioxide with and without a methanol modifier has been compared with a new portable cold extraction technique, phytosol solvent extraction (PSE), for the extraction of Tanshinone IIA from Salvia miltiorrhiza bunge. High-performance liquid chromatography was used to analyse the extracts. The results show that the yield extracted by 10% methanol-modified supercritical carbon dioxide was the highest (0.038%, w/w) and the yields extracted by supercritical carbon dioxide at 60°C and 250 kg/cm2 and phytosol solvents (A,B and D) were similar (0.029-0.032%, w/w).
KW - Phytosol solvent extraction
KW - salvia miltiorrhiza
KW - supercritical fluid extraction
KW - tanshinone IIA
U2 - 10.1016/S0021-9673(97)01087-X
DO - 10.1016/S0021-9673(97)01087-X
M3 - Article
VL - 799
SP - 343
EP - 348
JO - Journal of Chromatography A
JF - Journal of Chromatography A
SN - 0021-9673
IS - 1-2
ER -