Factors Associated to Arterial Stiffness in Patients With Symptomatic Peripheral Artery Disease

Antonio Henrique Germano-Soares, Breno Quintella Farah, Aluísio Andrade-Lima, Wagner Ribeiro Domingues, Bruno Remígio Cavalcante, Marilia de Almeida Correia, Nelson Wolosker, Gabriel Grizzo Cucato, Raphael Mendes Ritti-Dias

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


BACKGROUND: The aim of this study was to identify the clinical factors associated with arterial stiffness in patients with symptomatic peripheral artery disease.

METHODS: In this cross-sectional study, 181 patients (67% men; mean aged 66 ± 9 years) were recruited and had their central arterial stiffness assessed by carotid-femoral pulse wave velocity (cf-PWV). Clinical characteristics are sociodemographic data, body mass index, comorbid conditions, and walking capacity.

RESULTS: Multiple linear regression analysis showed that age (b = 0.182, P = 0.032), body mass index (b = 0.254, P = 0.002), and mean blood pressure (b = 0.249, P = 0.021) were positively associated with cf-PWV.

CONCLUSIONS: Our results showed that the aging, elevated body mass index, and higher blood pressure are clinical factors associated with increased arterial stiffness in patients with peripheral artery disease.

Original languageEnglish
Pages (from-to)78-82
Number of pages5
JournalAnnals of Vascular Surgery
Early online date25 Jul 2019
Publication statusPublished - 1 Nov 2019
Externally publishedYes


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