TY - JOUR
T1 - Flexible Plasmonic Biosensors for Healthcare Monitoring
T2 - Progress and Prospects
AU - Song, Liping
AU - Chen, Jing
AU - Xu, Ben Bin
AU - Huang, Youju
N1 - Funding information: We gratefully acknowledge the financial supports from the National Natural Science Foundation of China (51873222, 52111530128, 52103325), the Zhejiang Provincial Natural Science Foundation of China (Z22B055324), the Key Research and Development Projects of Anhui Province (202004g01020016, 202104g01020009), the start-up funding from Hangzhou Normal University (4095C5021920452) and the Engineering and Physical Sciences Research Council (EPSRC) grant (EP/N007921/1).
PY - 2021/12/28
Y1 - 2021/12/28
N2 - The noble metal nanoparticle has been widely utilized as a plasmonic unit to enhance biosensor, by leveraging its electric and/or optical properties. Integrated with the ‘flexible’ feature, it further enables opportunities in developing healthcare products in a conformal and adaptive fashion, such as wrist pulse tracer, body temperature tracker, blood glucose monitor, etc. In this work, we present a holistic review of the recent advance of flexible plasmonic biosensors for the healthcare sector. The technical spectrum broadly covers the design and selection of flexible substrate, the process to integrate flexible and plasmonic units, the exploration of different type of flexible plasmonic biosensors to monitor human temperature, blood glucose, ions, gas, motion indicators, as well as their applications for Surface-enhanced Raman scattering (SERS) and colorimetric detections. Their fundamental working principles and structural innovations are scoped and summarised. The challenges and prospects are articulated regarding the critical importance for continued progress of flexible plasmonic biosensors to improve living quality.
AB - The noble metal nanoparticle has been widely utilized as a plasmonic unit to enhance biosensor, by leveraging its electric and/or optical properties. Integrated with the ‘flexible’ feature, it further enables opportunities in developing healthcare products in a conformal and adaptive fashion, such as wrist pulse tracer, body temperature tracker, blood glucose monitor, etc. In this work, we present a holistic review of the recent advance of flexible plasmonic biosensors for the healthcare sector. The technical spectrum broadly covers the design and selection of flexible substrate, the process to integrate flexible and plasmonic units, the exploration of different type of flexible plasmonic biosensors to monitor human temperature, blood glucose, ions, gas, motion indicators, as well as their applications for Surface-enhanced Raman scattering (SERS) and colorimetric detections. Their fundamental working principles and structural innovations are scoped and summarised. The challenges and prospects are articulated regarding the critical importance for continued progress of flexible plasmonic biosensors to improve living quality.
KW - plasmonic biosensors
KW - noble nanoparticles
KW - flexible
KW - wearable
KW - healthcare monitoring
KW - SERS
KW - electrochemical biosensors,
KW - colorimetric biosensors
KW - electrochemical biosensors
KW - General Materials Science
KW - General Engineering
KW - General Physics and Astronomy
UR - http://www.scopus.com/inward/record.url?scp=85120565968&partnerID=8YFLogxK
U2 - 10.1021/acsnano.1c07176
DO - 10.1021/acsnano.1c07176
M3 - Review article
SN - 1936-0851
VL - 15
SP - 18822
EP - 18847
JO - ACS Nano
JF - ACS Nano
IS - 12
ER -
