Fluostatins C~E, novel members of the fluostatin family produced by Streptomyces sp. Acta 1383

Stefanie Baur, Jörg Niehaus, Amalia Karagouni, Efstathios Katsifas, Kalliopi Chalkou, Christos Maintanis, Amanda Jones, Michael Goodfellow, Alan Ward, Winfried Beil, Kathrin Schneider, Roderich Süssmuth, Hans-Peter Fiedler

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

Three new members of the fluostatin family, fluostatins CE, were discovered in a culture filtrate extract of strain Acta 1383 during an HPLC screening program. The producing strain belongs to the genus Streptomyces and is closely related to type strains classified in the Streptomyces lavendulae 16S rRNA subclade. Fluostatins are named by their characteristic fluorenone chromophore. Fluostatin C shows moderate activity against selected human tumor cell lines.
Original languageEnglish
Pages (from-to)293-297
JournalJournal of Antibiotics
Volume59
DOIs
Publication statusPublished - 2006

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