TY - JOUR
T1 - Functional and Cardiovascular Measurements in Patients With Peripheral Artery Disease
T2 - Comparison Between Men and Women
AU - de Almeida Correia, Marilia
AU - de Sousa, Adilson Santos Andrade
AU - Andrade-Lima, Aluísio
AU - Germano-Soares, Antônio H
AU - Zerati, Antônio Eduardo
AU - Puech-Leão, Pedro
AU - Wolosker, Nelson
AU - Gardner, Andrew W
AU - Ritti-Dias, Raphael Mendes
AU - Cucato, Gabriel G
PY - 2020/1
Y1 - 2020/1
N2 - PURPOSE: To compare functional and cardiovascular variables of men and women with peripheral artery disease (PAD).METHODS: This observational, cross-sectional study included 67 women and 144 men (age 66 ± 9 and 67 ± 10 yr, respectively) with PAD. Patients were submitted to a clinical evaluation, 6-min walk test (6MWT) and cardiovascular evaluation, including blood pressure, arterial stiffness variables, and heart rate variability.RESULTS: Women had lower claudication onset distance (P = .033) and 6MWT distance (P < .001), and similar percentage of the predicted 6MWT distance (P > .05). Women had higher pulse pressure (P = .002), augmentation index (P < .001), augmentation index corrected by 75 bpm (P < .001), and brachial and central systolic blood pressure (P = .041 and P = .029). Diastolic blood pressure, pulse wave velocity, and heart rate variability were similar between sexes (P > .05).CONCLUSION: Although predicted 6MWT performance was similar between sexes, women had higher blood pressure and wave reflection variables compared with men. Interventions to reduce blood pressure and wave reflection should be emphasized in women with PAD.
AB - PURPOSE: To compare functional and cardiovascular variables of men and women with peripheral artery disease (PAD).METHODS: This observational, cross-sectional study included 67 women and 144 men (age 66 ± 9 and 67 ± 10 yr, respectively) with PAD. Patients were submitted to a clinical evaluation, 6-min walk test (6MWT) and cardiovascular evaluation, including blood pressure, arterial stiffness variables, and heart rate variability.RESULTS: Women had lower claudication onset distance (P = .033) and 6MWT distance (P < .001), and similar percentage of the predicted 6MWT distance (P > .05). Women had higher pulse pressure (P = .002), augmentation index (P < .001), augmentation index corrected by 75 bpm (P < .001), and brachial and central systolic blood pressure (P = .041 and P = .029). Diastolic blood pressure, pulse wave velocity, and heart rate variability were similar between sexes (P > .05).CONCLUSION: Although predicted 6MWT performance was similar between sexes, women had higher blood pressure and wave reflection variables compared with men. Interventions to reduce blood pressure and wave reflection should be emphasized in women with PAD.
KW - augmentation index
KW - blood pressure
KW - heart rate variability
KW - peripheral artery disease
KW - pulse wave velocity
KW - women
UR - http://www.scopus.com/inward/record.url?scp=85072775156&partnerID=8YFLogxK
U2 - 10.1097/HCR.0000000000000437
DO - 10.1097/HCR.0000000000000437
M3 - Article
C2 - 31348126
SN - 1932-7501
VL - 40
SP - 24
EP - 28
JO - Journal of Cardiopulmonary Rehabilitation and Prevention
JF - Journal of Cardiopulmonary Rehabilitation and Prevention
IS - 1
ER -