Fused Pyridine Derivatives from the Wittig Reaction of some Fluorinated Amides

Elliot Latham, Steven Murphy, Stephen Stanforth

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Compound 2 reacted with phosphorane 3 (R = Et) giving the quinoline derivative 5 whereas thiophenes 7 and 9 gave enamines 8 and 10 respectively with the appropriate phosphorane 3 (R = Me or Et). Pyridine derivative 11 yielded only ethyl 2-aminonicotinate with phosphorane 3 (R = Et). Compounds 8 and 10 gave the fused pyridine derivatives 14 and 15 respectively when treated with sodium hydride.
Original languageEnglish
Pages (from-to)10385-10388
JournalTetrahedron
Volume51
Issue number37
DOIs
Publication statusPublished - 11 Sep 1995

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